BIOF Supply High Quality Nefiracetam Powder CAS 77191-36-7 Nefiracetam

Short Description:

Nefiracetam is a nootropic drug that belongs to the racetam family. Here is an introduction to it:

Chemical Properties

• Nefiracetam has a chemical formula of C₁₇H₂₃NO₃. It is a white to off-white crystalline powder with a molecular weight of 289.37 g/mol.

Mechanism of Action

• Enhancing Neurotransmission: It modulates the activity of neurotransmitter receptors, particularly the AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors in the brain. By binding to these receptors, it potentiates the excitatory neurotransmission mediated by glutamate, which is crucial for learning, memory, and cognitive functions.

• Increasing Brain Metabolism: Nefiracetam can enhance cerebral blood flow and glucose metabolism in certain brain regions. This helps to provide more energy and nutrients to the neurons, promoting their normal function and synaptic plasticity.

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Cognitive Enhancement

• Memory Improvement: Nefiracetam plays a significant role in enhancing memory processes. It acts on the hippocampus, a brain region crucial for memory formation and retrieval. By modulating neurotransmitter systems and synaptic plasticity, it helps to improve both short-term and long-term memory, making it easier for individuals to learn and remember new information.

• Attention and Concentration: It has the ability to increase attention span and improve concentration. By regulating the activity of certain neurotransmitters, it helps to filter out distractions and allows individuals to focus better on tasks at hand, thus enhancing overall cognitive performance.

• Learning Facilitation: Nefiracetam facilitates the learning process by enhancing neural plasticity and promoting the formation of new synaptic connections in the brain. This makes it easier for individuals to acquire new knowledge and skills, and adapt to new learning situations.

Neuroprotective Effects

• Antioxidant Activity: It acts as an antioxidant, scavenging free radicals in the brain that can cause oxidative damage to neurons. By reducing oxidative stress, it helps to protect neurons from damage and degeneration, thereby maintaining the integrity of the nervous system.

• Preventing Excitotoxicity: Nefiracetam helps to prevent excitotoxicity, which is the excessive stimulation of neurons by excitatory neurotransmitters leading to cell death. By modulating neurotransmitter release and receptor activity, it keeps the excitatory-inhibitory balance in the brain, protecting neurons from potential damage.

Application

Cognitive Disorders

• Alzheimer's Disease: In the treatment of Alzheimer's disease, Nefiracetam can be used as an adjunct therapy to help improve cognitive symptoms such as memory loss, confusion, and disorientation. Although it cannot cure the disease, it may provide some relief and slow down the progression of cognitive decline in patients.

• Mild Cognitive Impairment: For individuals with mild cognitive impairment, Nefiracetam may be beneficial in improving cognitive function and preventing or delaying the progression to dementia. It can enhance memory and other cognitive abilities, allowing patients to maintain their daily activities and quality of life.

• Age-Related Cognitive Decline: As people age, cognitive function often declines. Nefiracetam can be used to help improve cognitive abilities in elderly individuals with age-related cognitive decline, such as memory problems, decreased attention, and slower thinking speed.

Neurological Conditions

• Post-Stroke Cognitive Deficits: After a stroke, many patients experience cognitive deficits due to brain damage. Nefiracetam can be used to improve cognitive function in these patients, helping them to recover better and regain their independence in daily life.

• Traumatic Brain Injury: In cases of traumatic brain injury, Nefiracetam's neuroprotective effects can help to reduce neuronal damage and promote cognitive recovery. It may improve memory, attention, and other cognitive functions in patients with traumatic brain injury, facilitating their rehabilitation process.