Product Introduction
Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins. Additionally, spermidine stimulates T4 polynucleotide kinase activity. It is involved in growth, development, and the stress response in plants.
Spermidine trihydrochloride is the hydrochloric acid neutralized salt of spermidine. Spermidine is a polyamine and a trivalent organic cation. It is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy. External supplementation of spermidine extends lifespan and health span across species, including in yeast, nematodes, flies and mice. Spermidine trihydrochloride is a more stable form because spermidine is very air sensitive.
Function
Spermidine trihydrochloride is a NOS1 inhibitor and NMDA and T4 activator. Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. It was in a structural and functional study of polyamines, where potassium and sodium ions were found to promote different effects when binding with polyamines. Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.
Certificate Of Analysis
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Product Name |
Spermidine Trihydrochloride |
Specification |
Company Standard |
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CAS No. |
Manufacture Date |
2024.5.24 |
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Quantity |
300KG |
Analysis Date |
2024.5.30 |
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Batch No. |
ES-240524 |
Expiry Date |
2026.5.23 |
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Items |
Specifications |
Results |
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Assay (HPLC) |
≥98% |
99.46% |
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Appearance |
White to off-white powder |
Complies |
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Odor |
Characteristic |
Complies |
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Identification |
1HNMR Confirms to Structure |
Complies |
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Melting Point |
257℃ ~ 259℃ |
257.5-258.9ºC |
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Loss on Drying |
≤ 1.0% |
0.41% |
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Residue on Ignition |
≤ 0.2% |
0.08% |
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Solubility |
Soluble in Water |
Complies |
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Heavy Metal |
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Total Heavy Metals |
≤ 10 ppm |
Complies |
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Lead (Pb) |
≤ 0.5 ppm |
Complies |
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Arsenic (As) |
≤ 0.5 ppm |
Complies |
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Cadmium (Cd) |
≤ 0.5 ppm |
Complies |
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Mercury (Hg) |
≤ 0.1 ppm |
Complies |
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Microbiological Test |
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Total Plate Count |
≤ 1000 CFU/g |
Complies |
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Yeast & Mold |
≤ 100 CFU/g |
Complies |
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E.Coli |
Absence |
Absence |
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Salmonella |
Absence |
Absence |
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Staphyloccus Aureus |
Absence |
Absence |
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Package |
Packed in plastic bag inside and aluminum foil bag outside. |
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Storage |
Store in a cool and dry place, keep away from strong light and heat. |
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Shelf Life |
Two years when properly stored. |
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Conclusion |
Sample Qualified. |
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Inspection personnel：Yan Li Review personnel：Lifen Zhang Authorized personnel：LeiLiu
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