High Quality Pure Polypodiodes Niponica Powder 20:1 Polypodium Leucotomos Extract for Sale

I. Skin - related Effects

1. Photoprotective Effect
- Alleviates ultraviolet (UV) - induced skin damage. It can reduce UV - induced erythema and the formation of sunburn cells in the skin. It achieves this by absorbing and scattering ultraviolet rays and regulating antioxidant and immune - related signaling pathways in the skin.
2. Improvement of Skin Aging
- Reduces wrinkle depth and skin roughness. The active ingredients in Polypodium Leucotomos Extract (PLE) can inhibit the degradation of collagen and elastic fibers in the skin and stimulate fibroblasts to produce more collagen, thereby improving skin elasticity and firmness.
3. Adjuvant Treatment for Skin Diseases
- In the treatment of some inflammatory skin diseases such as psoriasis and atopic dermatitis, PLE can assist in reducing the inflammatory response. It regulates the activity of immune cells and reduces the release of inflammatory factors, relieving symptoms such as skin redness and itching.

II. Immunomodulatory Effects

1. Regulation of Immune Cell Activity
- Has a regulatory effect on the functions of immune cells such as lymphocytes and macrophages. It can inhibit overly active immune responses, prevent immune cells from attacking self - tissues in autoimmune diseases, and help maintain the balance of the immune system when fighting against foreign pathogen infections.
2. Anti - inflammatory Effect
- Reduces the inflammatory response in the body. By inhibiting inflammation - related signaling pathways, such as the NF - κB pathway, it reduces the production of inflammatory mediators such as interleukin - 1β and tumor necrosis factor - α, thus having potential application value in the prevention and treatment of various inflammatory diseases.