Factory Supply Succinic Acid Amber Acid Cas 110-15-6

Succinic acid yog dicarboxylic acid nrog cov tshuaj formula (CH2)2(CO2H)2.Lub npe muab los ntawm Latin succinum, lub ntsiab lus amber. Hauv cov kab mob muaj sia, succinic acid siv daim ntawv ntawm anion, succinate, uas muaj ntau lub luag haujlwm lom neeg raws li cov metabolic nruab nrab hloov mus rau hauv fumarate los ntawm enzyme succinate dehydrogenase nyob rau hauv complex 2 ntawm electron thauj saw uas koom nrog hauv kev ua ATP, thiab raws li succinic acid. ib tug signaling molecule reflecting lub cellular metabolic xeev. Succinate yog tsim nyob rau hauv mitochondria los ntawm lub voj voog tricarboxylic acid (TCA), cov txheej txheem ua kom muaj zog sib koom los ntawm txhua yam kab mob. Succinate tuaj yeem tawm ntawm mitochondrial matrix thiab ua haujlwm hauv cytoplasm nrog rau qhov chaw ntxiv ntawm tes, hloov cov qauv qhia cov noob, hloov kho epigenetic toj roob hauv pes lossis ua kom pom cov cim zoo li cov tshuaj hormones. Yog li ntawd, succinate txuas cellular metabolism, tshwj xeeb tshaj yog tsim ATP, mus rau kev tswj ntawm cellular muaj nuj nqi. Dysregulation ntawm succinate synthesis, thiab yog li ntawd ATP synthesis, tshwm sim nyob rau hauv qee yam kab mob mitochondrial, xws li Leigh syndrome, thiab Melas syndrome, thiab degradation tuaj yeem ua rau cov kab mob pathological, xws li malignant transformation, o thiab cov ntaub so ntswg raug mob.