Mmepụta Succinic Acid Amber Acid Cas 110-15-6

Succinic acid bụ dicarboxylic acid nwere usoro kemịkalụ (CH2)2(CO2H)2. Aha a sitere na Latin succinum, nke pụtara amber. N'ime ihe ndị dị ndụ, succinic acid na-ewere ụdị anion, succinate, nke nwere ọtụtụ ọrụ dị ndụ dị ka etiti nke metabolic na-agbanwe ka ọ bụrụ fumarate site na enzyme succinate dehydrogenase na mgbagwoju 2 nke eriri njem elektrọn nke na-etinye aka na ịme ATP, yana dịka molecule nke na-egosi ọnọdụ metabolic cellular. A na-emepụta succinate na mitochondria site na tricarboxylic acid cycle (TCA), usoro na-enye ume nke ihe niile dị ndụ na-ekekọrịta. Succinate nwere ike ịpụ na mitochondrial matriks wee rụọ ọrụ na cytoplasm yana oghere extracellular, na-agbanwe usoro okwu mkpụrụ ndụ ihe nketa, na-agbanwe ọdịdị ala epigenetic ma ọ bụ na-egosipụta akara ngosi homonụ. Dị ka nke a, succinate na-ejikọta metabolism cellular, karịsịa nhazi ATP, na nhazi nke ọrụ cellular. Dysregulation nke succinate njikọ, ya mere ATP njikọ, na-eme na ụfọdụ mkpụrụ ndụ ihe nketa mitochondrial ọrịa, dị ka Leigh syndrome, na Melas syndrome, na mmebi nwere ike iduga pathological ọnọdụ, dị ka malignant, mbufụt na anụ ahụ mmerụ.