NMN (aha zuru oke β-nicotinamide mononucleotide) - "C11H15N2O8P" bụ molekul na-apụta n'ụzọ nkịtị n'ụdị ndụ niile. Nucleotide bioactive a na-emekarị bụ ihe dị mkpa na mmepụta ume ma achọrọ maka usoro usoro ndu dị iche iche. Achọpụtala uru ọ bara n'ịkwalite ahụike na ogologo ndụ n'afọ ndị na-adịbeghị anya.
N'ọkwa molekul, NMN bụ ribonucleic acid, bụ isi ihe nhazi nke nucleus. E gosiputara na ọ na-arụ ọrụ enzyme sirtuin, nke na-arụ ọrụ dị mkpa na metabolism cellular na nhazi ike. Ejikọtala enzyme a na usoro mgbochi ịka nká, ebe ọ na-enyere aka nrụzi mmebi DNA na ihe ndị ọzọ dị na cellular nke na-eme n'onwe ya ka oge na-aga.
Na mgbakwunye na ọrụ ya na mmepụta ike cellular, NMN bụ ihe eji eme ihe na ịchọ mma. Ngwongwo ya na-egbochi mkpali na-eme ka ọ bụrụ ihe na-ewu ewu na ngwaahịa nlekọta anụ ahụ iji mee ka ahụ dị jụụ ma mezie akpụkpọ ahụ mebiri emebi. A na-ejikwa ya na ngwaahịa nlekọta ntutu iji nyere aka mee ka ntutu dị ike ma belata nkwụsị.
NMN na-apụtakarị dị ka ntụ ntụ kristal na-acha ọcha ma na-acha odo odo na-enweghị isi ísì. Chekwaa n'ebe kpọrọ nkụ na ụlọ okpomọkụ ma pụọ na ọkụ, yana ndụ nchekwa nke ọnwa 24. Mgbe ewere ya dị ka mgbakwunye.
Nnyocha n'ime uru ndị nwere ike ịnweta NMN ka na-aga n'ihu, mana nchọpụta mmalite na-egosi na ọ nwere ike ịbụ ngwá ọrụ dị irè maka ibelata ọdịda afọ metụtara ọrụ cellular na ịkwalite ahụike zuru oke. Dị ka mgbe niile, ọ dị mkpa ịkpọtụrụ onye na-ahụ maka ahụike iji chọpụta ma NMN ọ dị gị mma. Site na uru ahụike ya nwere ike na ihe omume okike n'ụdị ndụ niile, NMN bụ molekul nke ga-anọgide na-adọta uche nke ndị nyocha na ndị ọrụ.
Ngwa nke β-nicotinamide mononucleotide gụnyere:
Mgbochi ịka nká: β-nicotinamide mononucleotide mara na ọ na-arụ ọrụ sirtuins, nke bụ enzymes nke na-arụ ọrụ dị mkpa n'ịhazi ịka nká. A mụọla ya maka ike ya n'ịkwalite nrụzi cellular, melite ọrụ mitochondrial, na ịkwalite ogologo ndụ n'ozuzu ya.
Metabolism ike: β-nicotinamide mononucleotide bụ ihe mmalite nke nicotinamide adenine dinucleotide (NAD +), coenzyme na-etinye aka na usoro metabolic dị iche iche. Site na ịbawanye ọkwa NAD +, β-nicotinamide mononucleotide nwere ike ịkwado mmepụta ume na metabolism.
Neuroprotection: Nnyocha na-egosi na β-nicotinamide mononucleotide nwere ike inwe mmetụta neuroprotective site n'ịkwalite ọrụ cell na ichebe nrụgide oxidative na mbufụt. O gosiputara ikike n'ịgwọ ọrịa neurodegenerative metụtara afọ dịka Alzheimer na Parkinson.
Ahụike obi obi: β-nicotinamide mononucleotide enyochala maka ikike ọ nwere ime ka ahụike obi dịkwuo mma. Ọ nwere ike inye aka na-echebe megide nrụgide oxidative, mbufụt, na mmebi vaskụla, si otú ahụ belata ihe ize ndụ nke ọrịa obi.
Mmega ahụ: Ụfọdụ ọmụmụ na-atụ aro na β-nicotinamide mononucleotide nwere ike ịkwalite arụmọrụ na ntachi obi site na imeziwanye ọrụ mitochondrial na mmepụta ume.
Oge nzipu: Jul-04-2023
