Ọgbọ nke atọ nke Carnosine mmepụta: N-acetyl carnosine

N'akụkọ ihe mere eme nke China, a na-ewere akwụ nnụnụ dị ka tonic, nke a maara dị ka "Oriental Caviar". Edere ya na Materia Medica na akwụ nnụnụ bụ "ihe na-eme ka ọ dị ọcha ma nwee ike ịsacha ya, ọ bụkwa ọgwụ dị nsọ maka ịhazi ụkọ na ịrụ ọrụ". N-Acetyl Neuraminic Acid bụ isi ihe na-esi na akwụ nnụnụ, ya mere a na-akpọkwa ya acid akwu nnụnụ, ọdịnaya ya bụkwa ihe na-egosi ọkwa nnụnụ nnụnụ.

N-acetyl carnosine (NAC) bụ ihe sitere n'okike nke metụtara dipeptide carnosine. Usoro ihe omimi nke NAC yiri nke carnosine ma e wezụga na ọ na-ebu otu acetyl ọzọ. Acetylation na-eme ka NAC na-eguzogide mmebi site na myostatin, enzyme nke na-akụda myostatin n'ime amino acids β-alanine na histidine mejupụtara.

O-Acetyl Carnosine bụ ihe sitere n'okike nke carnosine bụ nke a chọpụtara na mbụ na anụ ahụ oke bekee na 1975. N'ime mmadụ, acetyl carnosine bụ isi na akwara skeletal, na anụ ahụ na-ewepụta akụkụ ahụ mgbe mmadụ na-emega ahụ.

Dị ka ọgbọ nke atọ nke ihe ndị na-emepụta carnosine eke, acetyl carnosine nwere ike n'ozuzu ike, acetylation mgbanwe na-eme ka ọ bụrụ na ọ na-eme ka ọ ghara ịdị na-amata ma mebie ya site na carnosine peptidase n'ime ahụ mmadụ, ma nwee nkwụsi ike dị elu. Ha nwere mmetụta doro anya na antioxidant, mgbochi glycation. , mgbochi mbufụt, wdg.

Acetyl carnosine abụghị naanị na-eme ka nkwụsi ike dịkwuo mma, kamakwa ọ na-eketa ezigbo antioxidant na mgbochi mkpali mmetụta nke carnosine.

Acetyl carnosine nwere ọtụtụ mmetụta, ọ bụghị naanị na ọ nwere ike igwu egwu na-agba ume, na-eme ka ahụ dị jụụ, na-ekpo ọkụ na mmetụta nlekọta anụ ahụ ndị ọzọ, kamakwa na-egbochi ọgbọ nke radicals free oxygen, ihe mkpali, ejirila ya mee ihe na ọgwụgwọ nke cataract mgbaàmà nke anya mmiri.

A na-ejikwa acetyl carnosine na ụfọdụ ihe ịchọ mma ma ọ bụ ngwaahịa nlekọta.Dịka ọmụmaatụ, ngwaahịa nlekọta anụ ahụ maka ihu, ahụ, olu, aka, na akpụkpọ anụ periocular; ngwaahịa mma na nlekọta (dịka ọmụmaatụ, lotions, ude AM/PM, serum); antioxidants, akpụkpọ anụ, ma ọ bụ moisturizers na ihe ịchọ mma na ngwaahịa nlekọta anụ ahụ; na ọgwụgwọ enhancers na ointments.

N'ịchịkọta, dị ka ihe na-emekarị na ahụ mmadụ, myostatin na ihe ndị na-emepụta ya nwere oke nchekwa dị elu.