Methyl 4-hydroxybenzoate Methylparaben imodzi mwa parabens, ndi mankhwala osungira ndi mankhwala formula CH3(C6H4(OH)COO). Ndi methyl ester ya p-hydroxybenzoic acid.
Methyl 4-hydroxybenzoate Methylparaben amagwira ntchito ngati pheromone kwa tizilombo tosiyanasiyana ndipo ndi gawo la mfumukazi mandibular pheromone.
Ndi pheromone mu mimbulu yopangidwa panthawi ya estrus yokhudzana ndi khalidwe la mimbulu yamphongo ya alpha yomwe imalepheretsa amuna ena kukwera akazi pa kutentha.
Methyl 4-hydroxybenzoate Methylparaben ndi mankhwala odana ndi mafangasi omwe amagwiritsidwa ntchito popanga zodzoladzola zosiyanasiyana komanso zinthu zodzisamalira. Amagwiritsidwanso ntchito ngati chosungira chakudya.
Methyl 4-hydroxybenzoate Methylparaben amagwiritsidwa ntchito ngati fungicide mu Drosophila media media pa 0.1%. Kwa Drosophila, methyl 4-hydroxybenzoate methylparaben imakhala yowopsa kwambiri, imakhala ndi mphamvu ya estrogenic (kutengera estrogen mu makoswe ndikukhala ndi anti-androgenic zochita), ndipo imachepetsa kukula kwa mphutsi ndi pupal pa 0.2%.
Pali mkangano wokhudza ngati methyl 4-hydroxybenzoate methylparaben kapena propylparabens ndi yovulaza pamagulu omwe amagwiritsidwa ntchito posamalira thupi kapena zodzoladzola. Methylparaben ndi propylparaben amadziwika kuti ndi otetezeka (GRAS) ndi USFDA poteteza chakudya ndi zodzikongoletsera. Methyl 4-hydroxybenzoate Methylparaben imapangidwa mosavuta ndi mabakiteriya wamba, ndikupangitsa kuti zisawonongeke.
Methyl 4-hydroxybenzoate Methylparaben imatengedwa mosavuta kuchokera m'matumbo a m'mimba kapena pakhungu. Imapangidwa ndi hydrolyzed kukhala p-hydroxybenzoic acid ndipo imatuluka mwachangu mumkodzo popanda kuwunjikana m'thupi. Kafukufuku woopsa wapoizoni wasonyeza kuti methylparaben siikhala poizoni poyang'anira pakamwa komanso pobereka nyama. Pa anthu omwe ali ndi khungu labwinobwino, methylparaben imakhala yosakwiyitsa komanso yosasangalatsa; komabe, kusagwirizana ndi ma parabens omwe amwedwa adanenedwa. Kafukufuku wa 2008 adapeza kuti palibe mpikisano wa anthu estrogen ndi androgen receptors a methylparaben, koma milingo yosiyanasiyana yomangiriza mpikisano idawonedwa ndi butyl- ndi isobutyl-paraben.
Kafukufuku akuwonetsa kuti methylparaben yomwe imagwiritsidwa ntchito pakhungu imatha kuchitapo kanthu ndi UVB, zomwe zimapangitsa kuti khungu lizikalamba komanso kuwonongeka kwa DNA.
Poyankha izi, mabungwe ena owongolera ndi mabungwe achitapo kanthu kuti aletse kugwiritsa ntchito methyl paraben pazinthu zina. Mwachitsanzo, European Union imachepetsa kuchuluka kwa methyl paraben yomwe imaloledwa mu zodzoladzola, ndipo opanga ena asankha kukonzanso zinthu zawo kuti zisakhale za paraben. Kuphatikiza apo, kufunikira kokulirapo kwa njira zachilengedwe komanso zachilengedwe m'malo mwa zosungira zakale zapangitsa kuti pakhale mapangidwe atsopano omwe alibe methyl paraben kapena ma parabens ena.
Methylparaben imayamikiridwa chifukwa cha kukhazikika kwake komanso kugwirizana ndi mitundu yosiyanasiyana. Nthawi zambiri sichisintha mtundu, fungo, kapena kapangidwe kazinthu zomwe zimagwiritsidwa ntchito, zomwe zimapangitsa kuti zikhale zotha kusintha kwa wopanga. Kukhazikika kumeneku kumakulitsa moyo wa alumali ndikuthandiza kusunga mtundu wonse wa mankhwalawa pakapita nthawi yayitali.
Ogula akuyenera kumvetsetsa kukhudzika kwawo komanso zomwe angakumane nazo akamagwiritsa ntchito mankhwala okhala ndi methylparaben. Ngakhale kuti methylparaben nthawi zambiri imatengedwa kuti ndi yotetezeka kuti igwiritsidwe ntchito muzodzoladzola, anthu ena amatha kupsa mtima pakhungu kapena kusagwirizana nawo. Nthawi zonse tikulimbikitsidwa kuyesa chigamba musanagwiritse ntchito chatsopano kuti muwone ngati pali vuto lililonse.
Pomaliza, methyl 4-hydroxybenzoate kapena methylparaben ndi mankhwala omwe amagwiritsidwa ntchito kwambiri m'mafakitale odzola ndi mankhwala. Ngakhale kutsutsana chifukwa cha nkhawa zokhudzana ndi momwe zingakhudzire kuchuluka kwa mahomoni komanso uchembere wabwino, imakhalabe chisankho chodziwika bwino pakusungidwa kwazinthu chifukwa champhamvu, kukhazikika, komanso kugwirizana ndi mitundu yosiyanasiyana. Pomwe kufunikira kwa zinthu zachilengedwe komanso zachilengedwe kukukulirakulira, kugwiritsa ntchito methylparaben kuyenera kusinthika ndipo zoteteza zina zitha kukhala zofala pamsika. Ogula ayenera kumvetsetsa zomwe zili muzinthu zomwe amagwiritsa ntchito ndikupanga zisankho zomwe zimagwirizana ndi zomwe amakonda komanso zomwe amakonda.
Nthawi yotumiza: Apr-19-2024