Gutanga Uruganda Acide Acide Amber Acide Cas 110-15-6

Acide Succinic ni aside ya dicarboxylic hamwe na formulaire ya chimique (CH2) 2 (CO2H) 2.Izina rikomoka kuri latine succinum, bisobanura amber. Mu binyabuzima bizima, acide succinic ifata ishusho ya anion, succinc, ifite uruhare runini rwibinyabuzima nkigihe cyo guhinduranya metabolike ihinduka fumarate na enzyme succinate dehydrogenase muri complexe 2 yumurongo wa transport wa elegitoronike ugira uruhare mugukora ATP, kandi nka molekile yerekana ibimenyetso byimikorere ya selile. Succinate ikorwa muri mitochondriya ikoresheje aside irike ya tricarboxylic (TCA), inzira itanga ingufu ihuriweho n’ibinyabuzima byose. Succinc irashobora kuva muri matrix ya mitochondrial kandi igakora muri cytoplazme kimwe n'umwanya udasanzwe, guhindura imiterere ya gene, guhindura imiterere ya epigenetike cyangwa kwerekana ibimenyetso bisa na hormone. Nkibyo, guhuza guhuza metabolism selile, cyane cyane gushiraho ATP, kugenga imikorere ya selile. Kudakwirakwiza synthesis, bityo rero ATP synthesis, bibaho mu ndwara zimwe na zimwe za mitochondrial genetique, nka syndrome ya Leigh, na Melas syndrome, kandi kwangirika bishobora gutera indwara ziterwa na pathologiya, nko guhinduka nabi, gutwika no gukomeretsa ingirangingo.