Shakisha umutekano wa Methyl 4-hydroxybenzoate Methylparaben mubicuruzwa byawe bwite

Methyl 4-hydroxybenzoate Methylparaben imwe muri parabene, ni uburyo bwo kubungabunga imiti ya chimique CH3 (C6H4 (OH) COO). Ni methyl ester ya p-hydroxybenzoic aside.
Methyl 4-hydroxybenzoate Methylparaben ikora nka feromone y’udukoko dutandukanye kandi ni kimwe mu bigize umwamikazi mandibular feromone.
Ni feromone mu mpyisi ikorwa mugihe cya estrus ijyanye nimyitwarire yimpyisi ya alpha ibuza abandi bagabo gutera igitsina gore mubushuhe.
Methyl 4-hydroxybenzoate Methylparaben numuti urwanya fungal ukoreshwa mubintu bitandukanye byo kwisiga hamwe nibicuruzwa byita kumuntu. Ikoreshwa kandi muburyo bwo kubika ibiryo.
Methyl 4-hydroxybenzoate Methylparaben isanzwe ikoreshwa nka fungiside mubitangazamakuru byibiribwa bya Drosophila kuri 0.1%. Kuri Drosophila, methyl 4-hydroxybenzoate methylparaben ni uburozi murwego rwo hejuru, igira ingaruka ya estrogeneque (kwigana estrogene mu mbeba no kugira ibikorwa birwanya andorogene), kandi igabanya umuvuduko wo gukura mubyiciro bya nyababyeyi na 0.2%.
Hariho impaka zo kumenya niba methyl 4-hydroxybenzoate methylparaben cyangwa propylparabens byangiza mubitekerezo bikunze gukoreshwa mukubungabunga umubiri cyangwa kwisiga. Methylparaben na propylparaben bifatwa nkibisanzwe bizwi ko bifite umutekano (GRAS) na USFDA kubiribwa no kubungabunga antibacterial cosmetic. Methyl 4-hydroxybenzoate Methylparaben ihinduranya byoroshye na bagiteri zisanzwe zubutaka, bigatuma ibinyabuzima byangirika rwose.
Methyl 4-hydroxybenzoate Methylparaben ihita yinjira mu nzira ya gastrointestinal cyangwa binyuze mu ruhu. Ifite hydrolyzed kuri p-hydroxybenzoic aside kandi isohoka vuba muminkari itarundanyije mumubiri. Ubushakashatsi bukabije bw’uburozi bwerekanye ko methylparaben isanzwe idafite uburozi haba mu kanwa ndetse n’ababyeyi mu nyamaswa. Mu baturage bafite uruhu rusanzwe, methylparaben usanga idatera uburakari kandi idakangurira; icyakora, byavuzwe ko allergique yatewe na parabene yatewe. Ubushakashatsi bwakozwe mu mwaka wa 2008 bwerekanye ko nta guhuza amarushanwa ya estrogene ya muntu na reseptor ya metrogaraben, ariko urwego rutandukanye rwo guhuza amarushanwa rwagaragaye hamwe na butyl- na isobutyl-paraben.
Ubushakashatsi bwerekana ko methylparaben ikoreshwa kuruhu ishobora kwitwara UVB, bigatuma gusaza kwuruhu byangirika no kwangirika kwa ADN.
Mu rwego rwo gusubiza izo mpungenge, ibigo bimwe n’ubuyobozi n’imiryango byafashe ingamba zo kugabanya ikoreshwa rya methyl paraben mu bicuruzwa bimwe na bimwe. Kurugero, Umuryango w’ubumwe bw’ibihugu by’i Burayi ugabanya ubukana bwa methyl paraben yemerewe kwisiga, kandi bamwe mu bakora inganda bahisemo kuvugurura ibicuruzwa byabo kugira paraben. Byongeye kandi, kwiyongera gukenera ubundi buryo bwa kamere na organic kubishobora kubungabunga gakondo byatumye habaho iterambere ryibintu bishya bitarimo methyl paraben cyangwa izindi parabene.
Methylparaben itoneshwa kugirango ihamye kandi ihuze nuburyo butandukanye. Mubisanzwe ntabwo ihindura ibara, impumuro, cyangwa imiterere yibicuruzwa byakoreshejwe, bigatuma ibigize ibintu byinshi kubabikora. Uku gushikama kwagura ubuzima bwigihe kandi bifasha kugumana ubuziranenge bwibicuruzwa mugihe kirekire.

Abaguzi bagomba gusobanukirwa ibyiyumvo byabo bwite na allergie mugihe bakoresha ibicuruzwa birimo methylparaben. Nubwo methylparaben isanzwe ifatwa nkumutekano kugirango ikoreshwe mu kwisiga, abantu bamwe bashobora kurwara uruhu cyangwa reaction ya allergique. Buri gihe birasabwa gukora ikizamini mbere yo gukoresha ibicuruzwa bishya kugirango umenye niba hari ingaruka mbi zibaho.
Mu gusoza, methyl 4-hydroxybenzoate cyangwa methylparaben ni imiti ikoreshwa cyane mu nganda zo kwisiga n’imiti. Nubwo bitavugwaho rumwe kubera impungenge ziterwa n'ingaruka zishobora kugira ku misemburo ya hormone no ku buzima bw'imyororokere, iracyahitamo gukundwa cyane mu kubika ibicuruzwa bitewe n’imikorere yayo, itajegajega, kandi ihuza n’ibintu bitandukanye. Mugihe icyifuzo cyibicuruzwa kama n’ibinyabuzima bikomeje kwiyongera, ikoreshwa rya methylparaben rishobora guhinduka kandi ubundi buryo bwo kubungabunga ibidukikije bushobora kwigaragaza cyane ku isoko. Abaguzi bagomba gusobanukirwa ibiyigize mubicuruzwa bakoresha kandi bagahitamo guhuza nibyo bakunda hamwe nibibazo byabo.