Vitamine B3 —— Igira uruhare runini mu mbaraga

Metabolism
Vitamine B3, izwi kandi ku izina rya niacin, ni vitamine ishonga mu mazi igira uruhare runini mu buryo butandukanye bwo guhinduranya umubiri. Dore ingingo z'ingenzi kuri vitamine B3:
Imiterere ya Vitamine B3:
Niacin ibaho muburyo bubiri: acide nicotinic na nicotinamide. Imiterere yombi ibanziriza coenzymes igira uruhare runini muburyo bwo guhinduranya ingufu.
Imikorere:
Niacin ibanziriza coenzymes ebyiri: nicotinamide adenine dinucleotide (NAD) na nicotinamide adenine dinucleotide fosifate (NADP). Izi coenzymes zigira uruhare muri redox reaction, zigira uruhare runini mukubyara ingufu, gusana ADN, n'inzira zitandukanye.
Inkomoko ya Niacin:
Inkomoko y'ibiryo bya niacin harimo:
Inyama (cyane cyane inkoko, amafi, ninyama zinanutse)
Imbuto n'imbuto
Ibikomoka ku mata
Ibinyamisogwe (nk'ibishyimbo n'ibinyomoro)
Ibinyampeke
Imboga
Ibinyampeke bikomejwe
Ibingana na Niacin:
Niacin yibiribwa irashobora kugaragarira muburinganire bwa niacin (NE). NE imwe ihwanye na mg 1 ya niacin cyangwa 60 mg ya tryptophan, aside amine ishobora guhinduka niacine mumubiri.
Ibura:
Kubura niacin bikabije birashobora gutera indwara izwi nka pellagra, irangwa nibimenyetso nka dermatite, impiswi, guta umutwe, kandi, iyo itavuwe, urupfu. Pellagra ni gake mu bihugu byateye imbere ariko irashobora kugaragara mubantu bafite indyo yuzuye ya niacin.
Basabwa Amafaranga yo Kurya (RDA):
Gusabwa gufata buri munsi niacin biratandukana bitewe nimyaka, igitsina, nubuzima. RDA igaragarira muri miligarama ya niacin ihwanye (NE).
Ubuzima bwa Niacin n'umutima n'imitsi:
Niacin yakozweho ubushakashatsi ku nyungu zishobora kubaho mu buzima bw'umutima. Irashobora gufasha kongera urugero rwa lipoproteine ​​(HDL cyangwa “nziza”) ya cholesterol no kugabanya urugero rwa lipoproteine ​​(LDL cyangwa “mbi”) ya cholesterol. Nyamara, inyongera ya niacin kumutima nimiyoboro yimitsi igomba gukorwa ikurikiranwa nubuvuzi kubera ingaruka zishobora guterwa.
Niacin Flush:
Umubare munini wa niacin urashobora gutera ingaruka mbi izwi nka "niacin flush," irangwa no gutukura, ubushyuhe, no guhinda uruhu. Iki nigisubizo cyigihe gito kuri vasodilating ingaruka za niacin kandi ntabwo ari bibi.
Inyongera:
Kwiyongera kwa Niacin mubusanzwe ntabwo ari nkenerwa kubantu bafite indyo yuzuye. Ariko, mubihe bimwe na bimwe byubuvuzi cyangwa kugenzurwa nubuvuzi, hashobora gusabwa inyongera ya niacin.
Imikoranire n'imiti:
Niacin irashobora gukorana n'imiti imwe n'imwe, harimo imiti y'umuvuduko w'amaraso, imiti ya diyabete, na statine. Abantu bafata imiti bagomba kubaza abashinzwe ubuzima mbere yo gufata inyongera za niacin.
Kwemeza gufata niacine ihagije binyuze mumirire yuzuye ni ngombwa kubuzima rusange no mumikorere myiza ya metabolike. Mugihe harebwa ibyuzuzanya, bigomba gukorwa bayobowe ninzobere mubuzima.