Product Introduction
Thiamidol is a patented anti-pigment ingredient developed after more than ten years of research. This active ingredient innovation marks a turning point in research into pigment spot removal – the effect of thiamidol is targeted and reversible, so the products have been proven to be effective and safe. Prior to this research, it was not possible to develop an active ingredient that works so precisely. On the contrary, until then it was only possible to inhibit the distribution by e.g. niacianamides and other active ingredients. Niacianamide alone is not an inhibitor of human tyrosine and only interrupts the transmission of melanin.
Function
The whitening effect of Thiamidol is very significant:
1. Inhibition of human tyrosinase activity: Thiamidol is one of the strongest inhibitors of human tyrosinase activity currently known, which can inhibit melanin formation from the source.
2. Safe and mild: Thiamidol has no cytotoxicity and is a safe and mild whitening ingredient. Thiamidol has great advantages over other whitening ingredients.
3. Effectiveness: Thiamidol can effectively improve mild, moderate and severe melasma, and it can also effectively improve pigmentation spots and age spots.
Certificate Of Analysis
|
Product Name |
Thiamidol |
Specification |
Company Standard |
|
CAS No. |
1428450-95-6 |
Manufacture Date |
2024.7.20 |
|
Quantity |
100KG |
Analysis Date |
2024.7.27 |
|
Batch No. |
ES-240720 |
Expiry Date |
2026.7.19 |
|
Molecular weight |
278.33 |
Molecular symbol |
C₁₈H₂₃NO₃S |
|
Items |
Specifications |
Results |
|
|
Appearance |
White to off-white powder |
Complies |
|
|
Identification |
The retention time of the major peak of the sample solution corresponds to that of the standard solution |
Complies |
|
|
Water content |
≤1.0% |
0.20% |
|
|
Residual solvent (GC) |
Acetonitrile≤0.041% |
ND |
|
|
|
Dichloromethane≤0.06% |
ND |
|
|
|
Toluene≤0.089% |
ND |
|
|
|
Heptane≤0.5% |
60ppm |
|
|
|
Ethanol≤0.5% |
ND |
|
|
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Ethyl acetate≤0.5% |
1319ppm |
|
|
|
Acetic acid≤0.5% |
ND |
|
|
Related substance (HPLC) |
Single Impurity≤1.0% |
0.27% |
|
|
|
Total Impuritics≤2.0% |
0.44% |
|
|
Residue on Ignition |
≤0.5% |
0.03% |
|
|
Assay （HPLC） |
98.0%～102.0% |
98.5% |
|
|
Storage |
Store in an air tight container,protected from light. |
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Shelf life |
Two years when properly stored. |
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Conclusion |
Qualified. |
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Inspection personnel：Yan Li Review personnel：Lifen Zhang Authorized personnel：LeiLiu
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