Falegaosimea Succinic Acid Amber Acid Cas 110-15-6

Succinic acid o le dicarboxylic acid ma le fua fa'atatau (CH2)2(CO2H)2. O le igoa e sau mai le Latina succinum, o lona uiga o le amber. I meaola ola, succinic acid e foliga mai o se anion, succinate, lea e tele ana matafaioi faʻapitoa e avea o se metabolic intermediate e liua i le fumarate e le enzyme succinate dehydrogenase i le lavelave 2 o le filifili felauaiga eletise lea e aʻafia i le faia o ATP, ma pei o se mole faʻailoga e atagia ai le tulaga o le metabolic cell. Succinate e gaosia i le mitochondria e ala i le tricarboxylic acid cycle (TCA), o se faiga e maua ai le malosi e faʻasoa e meaola uma. Succinate e mafai ona alu ese mai le mitochondrial matrix ma galue i le cytoplasm faʻapea foʻi ma le extracellular space, suiga o faʻataʻitaʻiga faʻataʻitaʻiga, faʻaogaina le laufanua epigenetic poʻo le faʻaalia o le faʻailoga e pei o le hormone. E pei o lea, o le succinate e fesoʻotaʻi ai le metabolism cellular, aemaise lava le faʻavaeina o le ATP, i le faʻatonutonuina o galuega feaveaʻi. Dysregulation of succinate synthesis, ma o le mea lea o le ATP synthesis, e tupu i nisi faʻamaʻi mitochondrial genetic, e pei o le Leigh syndrome, ma Melas syndrome, ma le faʻaleagaina e mafai ona oʻo atu ai i tulaga faʻapitoa, e pei o suiga leaga, afaina ma manuʻa.