Ongorora kuchengetedzeka kweMethyl 4-hydroxybenzoate Methylparaben mune zvigadzirwa zvekuchengeta munhu

Methyl 4-hydroxybenzoate Methylparaben imwe yeparabens, inochengetedza ine kemikari formula CH3(C6H4(OH)COO). Ndiyo methyl ester yep-hydroxybenzoic acid.
Methyl 4-hydroxybenzoate Methylparaben inoshanda sepheromone yezvipembenene zvakasiyana-siyana uye inhengo ye queen mandibular pheromone.
Iyo pheromone mumhumhi inogadzirwa panguva yeestrus yakabatana nemaitiro ealpha mapere echirume kudzivirira vamwe varume kubva mukukwira vakadzi mukupisa.
Methyl 4-hydroxybenzoate Methylparaben is anti-fungal agent inowanzoshandiswa mumhando dzakasiyana dzezvizoro uye zvigadzirwa zvekuchengeta munhu. Inoshandiswawo sechikafu chekuchengetedza.
Methyl 4-hydroxybenzoate Methylparaben inowanzoshandiswa se fungicide mu Drosophila food media pa 0.1%. KuDrosophila, methyl 4-hydroxybenzoate methylparaben ine chepfu panzvimbo yakakwirira, ine estrogenic effect (kutevedzera estrogen mumakonzo uye kuva ne-anti-androgenic chiitiko), uye inoderedza kukura kwekukura mumatanho ehuta uye pupal pa 0.2%.
Pane kukakavara pamusoro pekuti methyl 4-hydroxybenzoate methylparaben kana propylparabens inokuvadza pakudzika kunowanzo shandiswa mukuchengeta muviri kana zvizoro. Methylparaben uye propylparaben inoonekwa seyakachengeteka (GRAS) neUSFDA yechikafu uye yekuzora inodzivirira antibacterial kuchengetedza. Methyl 4-hydroxybenzoate Methylparaben inogadzikiswa nyore nyore nemabhakitiriya evhu akajairika, zvichiita kuti iparadze zvachose.
Methyl 4-hydroxybenzoate Methylparaben inotorwa nyore nyore kubva mudumbu kana kuburikidza neganda. Iyo hydrolyzed kune p-hydroxybenzoic acid uye inokurumidza kubuda muweti isina kuungana mumuviri. Acute toxicity zvidzidzo zvakaratidza kuti methylparaben inenge isiri-chepfu nemuromo uye parenteral kutonga mumhuka. Muhuwandu hwevanhu vane ganda rakakwana, methylparaben inenge isingasviki uye isinganzwisisi; zvisinei, allergic reactions kune akamedzwa parabens zvakataurwa. Chidzidzo che2008 chakawana pasina kukwikwidzana kusungirirwa kwevanhu estrogen uye androgen receptors yemethylparaben, asi mazinga akasiyana emakwikwi ekusunga akaonekwa nebutyl- uye isobutyl-paraben.
Zvidzidzo zvinoratidza kuti methylparaben inoshandiswa paganda inogona kuita neUVB, zvichiita kuti ganda riwedzere kukwegura uye kukuvara kweDNA.
Mukupindura kune izvi zvinonetsa, mamwe masangano anodzora uye masangano akatora matanho ekurambidza kushandiswa kwemethyl paraben mune zvimwe zvigadzirwa. Semuenzaniso, European Union inodzikamisa kuwanda kwemethyl paraben inobvumidzwa muzvizoro, uye vamwe vagadziri vakasarudza kugadzirisa zvigadzirwa zvavo kuti dzisaparabhen. Pamusoro pezvo, kudiwa kuri kukura kwechisikigo uye organic dzimwe nzira kune echinyakare kuchengetedza zvakakonzera kugadzirwa kwemaitiro matsva ayo asina methyl paraben kana mamwe maparabens.
Methylparaben inofarirwa nekugadzikana kwayo uye kuenderana neakasiyana magadzirirwo. Iyo kazhinji haishandure ruvara, kunhuwa, kana magadzirirwo ezvigadzirwa zvinoshandiswa, zvichiita kuti ive chinhu chinogoneka kumugadziri. Uku kugadzikana kunowedzera hupenyu hwesherufu uye kunobatsira kuchengetedza huwandu hwese hwechigadzirwa kwenguva refu.

Vatengi vanofanira kunzwisisa manzwiro avo ega uye zvinogona kuitika kana vachishandisa zvigadzirwa zvine methylparaben. Kunyange zvazvo methylparaben inowanzoonekwa yakachengeteka kuti ishandiswe muzvizoro, vamwe vanhu vanogona kusangana nekutsamwa kweganda kana kusawirirana. Zvinogara zvichikurudzirwa kuita chigamba bvunzo usati washandisa chigadzirwa chitsva kuti uone kana paine kukanganisa kwakaitika.
Mukupedzisa, methyl 4-hydroxybenzoate kana methylparaben inochengetedza inoshandiswa zvakanyanya mumaindasitiri ezvekuzora uye emishonga. Kunyangwe kukakavara nekuda kwekunetsekana pamusoro pezvinogona kuitika pamazinga ehomoni uye hutano hwekubereka, inoramba iri sarudzo yakakurumbira yekuchengetedza chigadzirwa nekuda kwekushanda kwayo, kugadzikana, uye kuenderana neakasiyana magadzirirwo. Sezvo kudiwa kwezvigadzirwa zvechisikigo uye organic kuri kuramba kuchikura, kushandiswa kwemethylparaben kungango shanduka uye dzimwe nzira dzekuchengetedza dzinogona kuwanda mumusika. Vatengi vanofanirwa kunzwisisa zvinongedzo muzvigadzirwa zvavanoshandisa uye kuita sarudzo dzinoenderana nezvavanofarira uye zvinovanetsa.