Mumakore achangopfuura, kushandiswa kwemonobenzone semushonga weganda-depigmenting kwamutsa gakava rakakura mukati menharaunda dzekurapa uye dzedermatological. Kunyange zvichitaurwa nevamwe semushonga unoshanda wemamiriro akaita sevitiligo, vamwe vanosimudza kushushikana nezve kuchengetedzeka kwayo uye zvinogona kuitika.
Monobenzone, inozivikanwawo semonobenzyl ether yehydroquinone (MBEH), inhengo yedepigmenting inoshandiswa kurerutsa ganda nekuparadza zvachose melanocytes, masero anogadzira melanin. Iyi pfuma yakatungamira kushandiswa kwayo mukurapa vitiligo, chirwere chisingaperi cheganda chinoratidzwa nekurasikirwa kwepigmentation muzvigamba.
Vatsigiri vemonobenzone vanopokana kuti inogona kubatsira vanhu vane vitiligo kuwana ganda rakafanana nekubvisa pigment nzvimbo dzisina kukanganiswa kuti dzienderane nezvigamba zvakasvibiswa. Izvi zvinogona kuvandudza chitarisiko chese uye kuzviremekedza kweavo vanobatwa nemamiriro ezvinhu, izvo zvinogona kuita zvakakosha pamhando yehupenyu hwavo.
Zvisinei, kushandiswa kwe monobenzone hakusi pasina kukakavara. Vatsoropodzi vanonongedza kune zvinogona kukonzeresa uye zvine chekuita nekuchengetedza zvine chekuita nekushandiswa kwayo. Chimwe chezvinonyanya kunetsa injodzi yekusadzorereka depigmentation, sezvo monobenzone inoparadza zvachose melanocytes. Izvi zvinoreva kuti kana depigmentation ikaitika, haigoni kuchinjwa, uye ganda richaramba rakareruka munzvimbo idzodzo nekusingaperi.
Pamusoro pezvo, kune dhata renguva refu pamusoro pekuchengetedzwa kwemonobenzone, kunyanya zvine chekuita necarcinogenicity yayo uye njodzi yekunzwa kweganda uye kushatirwa. Zvimwe zvidzidzo zvakaratidza hukama hunogona kuitika pakati pekushandiswa kwemonobenzone uye kuwedzera kwengozi yekenza yeganda, kunyange zvazvo tsvakurudzo yakawanda ichidiwa kusimbisa izvi zvakawanikwa.
Uyezve, kukanganiswa kwepfungwa kwekubvisa pigmentation nemonobenzone hakufanirwe kufuratirwa. Kunyangwe ichigona kunatsiridza chitarisiko cheganda rine vitiligo, zvinogona zvakare kutungamirira kumanzwiro ekurasikirwa nekuzivikanwa uye kusarura kwetsika, kunyanya munharaunda umo ruvara rweganda rwakanyatsopindirana nekuzivikanwa uye kugamuchirwa munharaunda.
Pasinei nekunetseka uku, monobenzone inoramba ichishandiswa mukurapa vitiligo, zvisinei nekuchenjerera uye kunyatsotarisa kune zvakaipa. Vanachiremba veDermatologist nevatarisiri vehutano vanosimbisa kukosha kwekubvuma ruzivo uye dzidzo yemurwere yakakwana pavanenge vachifunga nezve monobenzone therapy, kuve nechokwadi chekuti vanhu vanonzwisisa zvese zvinogona kubatsira uye njodzi dzine chekuita nekushandiswa kwayo.
Kuenderera mberi, kumwe kutsvakurudza kunodiwa kuti tinzwisise zviri nani kuchengetedzwa kwenguva refu uye kushanda kwemonobenzone, pamwe chete nemigumisiro yaro pakugara zvakanaka kwepfungwa dzevarwere. Zvichakadaro, varapi vanofanira kuyera mabhenefiti nenjodzi dzemonobenzone therapy pane imwe nyaya-ne-case hwaro, vachifunga nezvezvakasiyana mamiriro emurwere uye zvaanoda.
Mukupedzisa, kushandiswa kwemonobenzone seganda-depigmenting agent inoramba iri musoro wekukakavadzana uye kukakavara mukati mehutano hwehutano. Kunyangwe ichigona kupa mabhenefiti kune vanhu vane vitiligo, kunetseka nezve kuchengetedzwa kwayo uye mhedzisiro yenguva refu inosimbisa kukosha kwekunyatsotariswa uye kutarisa kana uchishandisa mumiriri uyu mukudzidzira kwekiriniki.
Nguva yekutumira: Kurume-09-2024
