Ceramide imhando yeamide makomisheni anoumbwa nekuderera kwemvura yeakareba-chain fatty acids uye amino boka re sphingomyelin, kunyanya ceramide phosphorylcholine uye ceramide phosphatidylethanolamine, phospholipids ndizvo zvinonyanya zvikamu zve cell membranes, uye 40% -50% ye sebum. iyo stratum corneum ine ceramides, ayo ari iwo chikamu chikuru che-inter-cellular matrix, uye kutamba a Inoita basa rinokosha pakuchengetedza kuenzana kwemvura ye stratum corneum. Ceramide ine simba rakasimba rekusunga mamorekuru emvura, uye inochengetedza hunyoro hweganda nekugadzira mesh chimiro mu stratum corneum. Nokudaro, ceramide inokwanisa kuchengetedza unyoro hweganda.
Ceramide (Cers) iripo mumasero ese eukaryotic uye inoita basa rakakosha mukutonga kwekusiyanisa masero, kupararira, apoptosis, kuchembera uye mamwe mabasa ehupenyu. Sezvo chikamu chikuru che intercellular lipids mu stratum corneum yeganda, ceramide haingoite semutumwa wechipiri molecule mumugwagwa we sphingomyelin, asiwo inoita basa rinokosha mukugadzirisa epidermal stratum corneum formation, iyo ine basa rekuchengetedza. iyo inodzivirira ganda, kunyorova, anti-kuchembera, kuchena, uye kurapwa kwechirwere.
Heano mamwe akakosha pfungwa nezve ceramides:
Chimiro Chekuita
Ceramide chikamu chikuru cheiyo lipid bilayers mumasero membranes, uye inonyanya kuwanda mukunze kweganda. Mu stratum corneum, ceramide inobatsira kuumba chidziviriro chekudzivirira chinodzivirira kurasikirwa kwemvura uye chinodzivirira ganda kubva kune zvinosvibisa kunze.
Skin Barrier Function
Iyo stratum corneum inoshanda sechipinganidzo kune yekunze nharaunda, uye kuumbwa kwemaceramides mune iyi layer kwakakosha pakuchengetedza ganda hydration uye kudzivirira kupinda kwezvinhu zvinokuvadza. Kushaikwa kwemaceramide kunogona kutungamirira kune yakaoma ganda uye kukanganisa barriers basa.
Kukwegura uye Mamiriro Eganda
Iwo mazinga emaceramide paganda anowanzo kuderera nezera, uye kuderera uku kunobatana nemamiriro ezvinhu akadai seganda rakaoma uye makwinya. Mune mamwe mamiriro eganda, senge eczema, psoriasis, uye atopic dermatitis, panogona kuve nekukanganisa mukuumbwa kweceramide, zvichikonzera kurwara kwemamiriro aya.
Cosmetic uye Dermatological Applications
Tichifunga nezve basa ravo muhutano hweganda, maceramide anowanzo kuverengerwa muzvigadzirwa zvekuchengetedza ganda. Topical application yemaceramide inogona kubatsira kudzoreredza uye kuchengetedza ganda rinodzivirira, rinogona kubatsira vanhu vane ganda rakaoma kana rakakanganiswa.
Mhando dzeCeramides
Kune akati wandei marudzi emakeramidhi (akasarudzwa nenhamba dzakadai seCeramide 1, Ceramide 2, zvichingodaro), uye mhando yega yega ine chimiro chakati siyanei. Aya marudzi akasiyana eceramide anogona kunge aine mabasa chaiwo paganda.
Dietary Sources
Nepo maceramide achinyanya kugadzirwa mumuviri, kumwe kutsvagisa kunoratidza kuti zvimwe zvikamu zvekudya, senge sphingolipids zvinowanikwa mune zvimwe zvikafu zvakaita semazai, zvinogona kubatsira kumazinga eceramide.
Nguva yekutumira: Zvita-12-2023
