Tartaric acid, inozivikanwawo se'kojic acid' kana 'kojic acid', chigadzirwa chemicrobial fermentation chinowanikwa musoya soya, soya bean paste, kubika waini, uye inogona kuwanikwa mune zvakawanda zvakaviriswa zvigadzirwa zvakaviriswa neAspergillus.
Masayendisiti ekutanga akawana kuti maoko evashandi vechikadzi vedoro akanyanya kuchena. Mushure mekudzidza kwezvigadzirwa zvekuvirisa, zvakaonekwa kuti kwete chete ine basa rakanaka mukuchengetedza kutsva kweiyo curvilinear acid. Iyo inewo yakanaka kuchena uye kupenya maitiro. Kunyange, toni yeganda haisi kunetseka. Vazhinji veEuropean neAmerica dermatologists vanoshandisa 2 kusvika 4% yekojic acid kurapa chloasma muvarwere vavo nemigumisiro yakanaka.
Kojic acid inogona kutadzisa kuita kwetyrosinase uye kumisa kugadzirwa kwe melanin. Kojic acid pamusangano we 20 μg/ml inogona kuvharidzira basa remazhinji tyrosinase enzymes ne 70% -80%. Muzvizoro, zvinokurudzirwa kuwedzera 0.5% -2% ye tretinoin, iyo inogona kutadzisa kugadzirwa kwe melanin uye kuwana mhedzisiro yekuchena uye mavara akareruka.
Pamusoro pekuita kuchena kwayo, kojic acid ine mahara radical scavenging uye antioxidant zvimiro. Inogona kubatsira astringent ganda, kukurudzira protein aggregation uye kuomesa ganda. Haisi chete ine mamwe antibacterial properties, asiwo ine humwe hunyoro hwekunyorova uye inogona kushandiswa sekuchengetedza chikafu uye zvizorwa. Kkojic asidhi inogona kuvharidzira basa re hyaluronidase, kuitira kuti inogonawo kuvharidzira allergies.
Kojic acid, yakafanana neVC, inosunga ions yemhangura uye inactivates tyrosinase.
Kojic acid inotadzisawo kugadzirwa kwe melanin oxidation intermediates. Kojic acid inonzi oxidised nechepakati dopaquinone, nokudaro kuderedza chain reaction substrate uye kudzivisa kutendeuka kwe melanin yepakati kubva pa dopaquinone fomu kusvika kune yekupedzisira melanin. Kudzika kwakadzika kunokwanisa kuwana mhedzisiro yakanaka nekuda kwechisimba chayo . Imhaka yekuti mhedzisiro yacho yakasimba zvekuti inogona kutungamira mukutsvuka kweganda uye kubata dermatitis. Nekuda kweizvozvo, ndosaka zvigadzirwa zvakawanda zvekuchena zvine zvakaderera zvekuwedzera.
Zvakanakira kojic acid zvakakwirira transdermal absorption, yakanaka tyrosinase inhibition uye hapana cytotoxic athari. Inogona kushandiswa kuchena, kubvisa mavara, kuvandudzwa kweganda, nezvimwewo; uye inogona kuwedzera kuchengetedza mvura uye kuwedzera elasticity yeganda.
Paunenge uchishandisa kojic acid, zviri nani kuterera kune zvinotevera pfungwa.
Kutanga, kojic acid ichakundikana muchiedza chakajeka kana nzvimbo dzakasimba dzine acidic uye panzvimbo pacho kuwedzera melanin.Saka, zvinokurudzirwa kuti kojic acid zvigadzirwa zvinonyanya kushandiswa chete usiku.
Chechipiri, kudzivisa kushandiswa kwe salicylic acid, michero acids, high concentration yeVC nezvimwe zvinhu. Zviri nyore kudarika-kukurudzira ganda uye kukunguruka uye kuparadza chipingamupinyi kuburikidza nekugadzirisa zvinhu zvine simba zvakanyanya zvinogumbura.Chechitatu, zvinoda kuita hydration yakasimba, teerera kune sunscreen kudzivirira anti-black.
Kunyange zvazvo kojic acid iri ace iri mugomba munyika inocheneruka, inoda kushandiswa nokungwarira uye kushandiswa zvakanaka kuitira kuti iite basa rinokosha.
Nguva yekutumira: Jun-08-2024
