Vitamin B1 - Cofactors yeHuman Energy Metabolism

Vitamin B1, inozivikanwawo se thiamine, ivhitamini inonyungudika mumvura inoita basa rakakosha mumetabolism yemacarbohydrates. Heano mazano anokosha pamusoro pevhitamini B1:
Chemical Structure:
Thiamine inonyungudika mumvura B-vitamini ine chimiro chemakemikari inosanganisira thiazole uye pyrimidine ring. Inowanikwa mune akati wandei, ine thiamine pyrophosphate (TPP) iri iyo inoshanda coenzyme fomu.
Basa:
Thiamine yakakosha pakushandurwa kwemacarbohydrates kuita simba. Inoshanda se coenzyme mune akati wandei akakosha biochemical maitiro anobatanidzwa mukuparara kweglucose.
Inobata basa rakakosha mukushanda kwemasero etsinga uye yakakosha pakushanda kwakaringana kwetsinga.
Kwakabva
Zvokudya zvakanaka zvethiamine zvinosanganisira zviyo, zviyo zvakasimbiswa, nyemba (sebhinzi nenyemba), nzungu, mhodzi, nyama yenguruve, uye mbiriso.
Kushomeka:
Kushaikwa kweThiamine kunogona kutungamirira kune chirwere chinonzi beriberi. Kune marudzi maviri makuru eberiberi:
Wet Beriberi:Inosanganisira zviratidzo zvemoyo uye zvinogona kutungamirira kumoyo kukundikana.
Dry Beriberi:Inokanganisa hurongwa hwemitsipa, huchitungamirira kune zviratidzo zvakadai sekushaya simba kwemhasuru, kurira, uye kuoma kufamba.
Kushaikwa kweThiamine kunogonawo kuitika muvanhu vanodya chikafu chakanyanya mumacarbohydrates akacheneswa uye kushomeka kwechikafu chine thiamine.
Mamiriro Akabatanidzwa neThiamine Kushaya:
Kugara kudhakwa ndicho chikonzero chinowanzokonzera kushomeka kwethiamine. Mamiriro acho anozivikanwa seWernicke-Korsakoff syndrome, uye anogona kutungamirira kune zvakakomba zviratidzo zvetsinga.
Mamiriro ezvinhu anokanganisa kunwa kwechikafu, senge chirwere cheCrohn kana kuvhiyiwa kwebariatric, zvinogona kuwedzera njodzi yekushaikwa kwethiamine.
Inokurudzirwa Daily Allowance (RDA):
Iyo inokurudzirwa yezuva nezuva yekutora thiamine inosiyana nezera, bonde, uye nhanho yehupenyu. Inoratidzwa mumilligrams.
Supplementation:
Thiamine supplementation inowanzokurudzirwa mumamiriro ekushayikwa kana kana pane kuwedzera kudiwa, zvakadai sepamuviri kana lactation. Iyo zvakare dzimwe nguva inonyorerwa kune vanhu vane mamwe mamiriro ekurapa.
Kunzwa Kupisa:
Thiamine inonzwa nekupisa. Kubika nekugadzirisa zvinogona kutungamira mukurasikirwa kwethiamine muchikafu. Naizvozvo, zvakakosha kusanganisa zvikafu zvakasiyana-siyana zvitsva uye zvishoma zvakagadziriswa mukudya kuti uve nechokwadi chekudya kwakakwana.
Kudyidzana neMishonga:
Mimwe mishonga, yakadai semamwe madiuretics uye anti-seizure mishonga, inogona kuwedzera kudiwa kwemuviri kwethiamine. Zvakakosha kubvunza nyanzvi yezvehutano kana paine zviri kunetsa pamusoro pechimiro chethiamine, kunyanya maererano nekushandiswa kwemishonga.
Kuve nechokwadi chekudya kwakakwana kwethiamine kuburikidza nekudya kwakakwana kwakakosha kune hutano hwese, kunyanya pakushanda kwakaringana kwetsinga system uye simba metabolism. Kana paine zviri kunetsa pamusoro pekushaikwa kwethiamine kana kuwedzera, zvinokurudzirwa kubvunza nyanzvi yezvehutano kuti uwane hutungamiriri hwemunhu.