Keenitaanka Warshada Succinic Acid Amber Acid Cas 110-15-6

Succinic acid waa dicarboxylic acid oo leh qaacido kiimikaad (CH2)2(CO2H)2.Magaca waxa uu ka yimid Latin succinum, oo macneheedu yahay amber. noolaha noolaha, succinic acid waxa uu qaataa qaabka anion, succinate, kaas oo leh doorar badan oo bayooloji ah sida dhexdhexaadiyaha dheef-shiid kiimikaadka oo loo beddelo fumarate by enzyme succinate dehydrogenase ee kakan 2 ee silsiladda gaadiidka elektaroonigga ah ee ku lug leh samaynta ATP, iyo sida molecule calaamad ah oo ka tarjumaysa xaaladda dheef-shiid kiimikaadka gacanta. Succinate waxa lagu abuuraa mitochondria iyada oo loo sii marayo wareegga tricarboxylic acid (TCA), habka tamarta-wax-soo-saarka ee ay wadaagaan dhammaan noolaha. Succinate waxay ka bixi kartaa mitirka mitochondrial waxayna ka shaqeysaa cytoplasmka iyo sidoo kale booska ka baxsan unugyada, beddelka qaababka muujinta hidda-wadaha, beddelaadda muuqaalka epigenetic ama muujinta calaamadaha hormoonka. Sidan oo kale, succinate waxay ku xidhaa dheef-shiid kiimikaad gacanta, gaar ahaan samaynta ATP, habaynta shaqada gacanta. Qalabaynta isku-dhafka succinate, oo sidaas darteed isku-dhafka ATP, wuxuu ku dhacaa cudurrada mitirka mitirka qaarkood, sida Leigh syndrome, iyo Melas syndrome, iyo hoos u dhaca waxay u horseedi kartaa xaalado pathological, sida isbeddel xun, caabuq iyo dhaawaca unugyada.