Lekola polokeho ea Methyl 4-hydroxybenzoate Methylparaben lihlahisoa tsa tlhokomelo ea motho

Methyl 4-hydroxybenzoate Methylparaben e 'ngoe ea li-parabens, ke se sireletsang se nang le foromo ea lik'hemik'hale CH3(C6H4(OH)COO). Ke methyl ester ea p-hydroxybenzoic acid.
Methyl 4-hydroxybenzoate Methylparaben e sebetsa joalo ka pheromone bakeng sa mefuta e fapaneng ea likokoanyana mme ke karolo ea mofumahali mandibular pheromone.
Ke pheromone ho liphiri tse hlahisoang nakong ea estrus e amanang le boits'oaro ba liphiri tse tona tsa alpha tse thibelang tse ling tse tona ho tloha ho tse tšehali mochesong.
Methyl 4-hydroxybenzoate Methylparaben ke anti-fungal agent e atisang ho sebelisoa mefuteng e fapaneng ea litlolo le lihlahisoa tsa tlhokomelo ea motho. E boetse e sebelisoa e le ntho e bolokang lijo.
Methyl 4-hydroxybenzoate Methylparaben e atisa ho sebelisoa e le sebolaea-khuru mecheng ea lijo tsa Drosophila ho 0.1%. Ho Drosophila, methyl 4-hydroxybenzoate methylparaben e chefo maemong a holimo, e na le phello ea estrogenic (ho etsisa estrogen ho likhoto le ho ba le ts'ebetso e khahlanong le androgenic), 'me e liehisa sekhahla sa kholo methating ea larval le pupal ho 0.2%.
Ho na le phehisano mabapi le hore na methyl 4-hydroxybenzoate methylparaben kapa propylparabens e kotsi maemong a tloaelehileng a sebelisoang tlhokomelong ea 'mele kapa litlolo. Methylparaben le propylparaben li nkuoa li amoheloa ka kakaretso li bolokehile (GRAS) ke USFDA bakeng sa ho boloka lijo le litlolo tsa antibacterial. Methyl 4-hydroxybenzoate Methylparaben e sebelisoa habonolo ke likokoana-hloko tse tloaelehileng tsa mobu, e leng se etsang hore e senyehe ka ho feletseng.
Methyl 4-hydroxybenzoate Methylparaben e monyela habonolo ho tsoa pampiring ea mala kapa ka letlalo. E na le hydrolyzed ho p-hydroxybenzoic acid 'me e ntšoa ka potlako morong ntle le ho bokellana' meleng. Liphuputso tse matla tsa chefo li bontšitse hore methylparaben ha e na chefo ka bobeli ba molomo le tsamaiso ea batsoali ho liphoofolo. Sebakeng sa baahi ba nang le letlalo le tloaelehileng, methylparaben e batla e sa halefise ebile ha e na maikutlo; leha ho le joalo, ho tlalehiloe ho hanana le li-parabens tse nooang. Phuputso ea 2008 ha ea ka ea fumana tlhōlisano ea tlhōlisano bakeng sa estrogen ea motho le li-receptor tsa androgen bakeng sa methylparaben, empa maemo a sa tšoaneng a tlhōlisano ea tlhōlisano a ile a bonoa ka butyl- le isobutyl-paraben.
Liphuputso li bontša hore methylparaben e sebelisoang letlalong e ka 'na ea itšoara ka UVB, e lebisang ho tsofala ha letlalo le ho senyeha ha DNA.
E le ho arabela litabeng tsena, mekhatlo e meng ea tsamaiso le mekhatlo e nkile mehato ea ho thibela tšebeliso ea methyl paraben lihlahisoa tse itseng. Ka mohlala, European Union e fokotsa khatello ea methyl paraben e lumelletsoeng litlolo, 'me bahlahisi ba bang ba khethile ho fetola lihlahisoa tsa bona hore li se ke tsa hlola li e-ba le paraben. Ho feta moo, tlhokahalo e ntseng e eketseha ea mefuta e meng ea tlhaho le ea tlhaho ho li-preservatives tsa setso e lebisitse ho nts'etsopele ea mefuta e mecha e se nang methyl paraben kapa li-parabens tse ling.
Methylparaben e ratoa ka lebaka la botsitso le ho lumellana ha eona le mefuta e sa tšoaneng ea metsoako. Ha e le hantle ha e fetole 'mala, monko, kapa sebopeho sa lihlahisoa tse sebelisitsoeng, e leng se etsang hore e be motsoako o fapaneng bakeng sa moetsi. Botsitso bona bo lelefatsa bophelo ba lishelefo 'me bo thusa ho boloka boleng ba kakaretso ba sehlahisoa ka nako e telele.

Bareki ba tlameha ho utloisisa kutloelo-bohloko ea bona le lintho tse ka bang teng ha ba sebelisa lihlahisoa tse nang le methylparaben. Le hoja ka kakaretso methylparaben e nkoa e sireletsehile bakeng sa tšebeliso ea litlolo, batho ba bang ba ka 'na ba e-ba le ho teneha ha letlalo kapa ho itšoara hantle. Kamehla ho khothaletsoa ho etsa tlhahlobo ea patch pele u sebelisa sehlahisoa se secha ho fumana hore na ho na le litlamorao tse mpe.
Qetellong, methyl 4-hydroxybenzoate kapa methylparaben ke setlolo se sebelisoang haholo liindastering tsa litlolo le tsa meriana. Le hoja e le tsekisanoang ka lebaka la ho ameha ka liphello tsa eona tse ka 'nang tsa e-ba teng maemong a li-hormone le bophelo bo botle ba ho ba le bana, e ntse e le khetho e tummeng bakeng sa ho boloka sehlahisoa ka lebaka la katleho ea eona, botsitso le ho lumellana le mefuta e sa tšoaneng ea metsoako. Ha tlhokahalo ea lihlahisoa tsa tlhaho le tsa tlhaho e ntse e hōla, tšebeliso ea methylparaben e ka 'na ea fetoha' me mefuta e meng ea li-preservative e ka 'na ea ata haholo' marakeng. Bareki ba tlameha ho utloisisa metsoako ea lihlahisoa tseo ba li sebelisang le ho etsa khetho e lumellanang le likhetho tsa bona le lintho tseo ba amehileng ka tsona.

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Nako ea poso: Apr-19-2024
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