NMN (lebitso le feletseng β-nicotinamide mononucleotide) - "C11H15N2O8P" ke molek'hule e hlahang ka tlhaho mefuteng eohle ea bophelo. Nucleotide ena ea tlhaho ea tlhaho ke ntho ea bohlokoa tlhahisong ea matla 'me e hlokahala bakeng sa mekhoa e fapaneng ea likokoana-hloko. Melemo ea eona e ka bang teng ho holiseng bophelo bo botle le ho phela nako e telele e 'nile ea ithutoa haholo lilemong tsa morao tjena.
Boemong ba limolek'hule, NMN ke ribonucleic acid, karolo ea motheo ea motheo ea nucleus. Ho bontšitsoe ho kenya tšebetsong enzyme sirtuin, e bapalang karolo ea bohlokoa ho metabolism ea cellular le taolo ea matla. Enzyme ena e boetse e amahanngoa le mekhoa e thibelang botsofali, kaha e thusa ho lokisa tšenyo ea DNA le likarolo tse ling tsa lisele tse hlahang ka tlhaho ha nako e ntse e ea.
Ntle le karolo ea eona ea tlhahiso ea matla a cellular, NMN ke motsoako oa litlolo. Lintho tsa eona tse thibelang ho ruruha li etsa hore e be motsoako o tsebahalang lihlahisoa tsa tlhokomelo ea letlalo ho thoba le ho lokisa letlalo le senyehileng. E boetse e sebelisoa ka tloaelo lihlahisoa tsa tlhokomelo ea moriri ho thusa ho matlafatsa moriri le ho fokotsa ho senya.
Hangata NMN e bonahala e le phofo e tšoeu ea kristale e mosehla ho isa ho e mosehla e se nang monko o bonahalang. Boloka sebakeng se omileng ka mocheso oa kamore le hole le leseli, ka nako ea bophelo ba likhoeli tse 24. Ha e nkoa e le tlatsetso.
Lipatlisiso mabapi le melemo e ka 'nang ea e-ba teng ea NMN li ntse li tsoela pele, empa liphuputso tsa pele li fana ka maikutlo a hore e ka' na ea e-ba sesebelisoa se sebetsang sa ho fokotsa ho fokotseha ho amanang le lilemo tsa mosebetsi oa cellular le ho khothalletsa bophelo bo botle ka kakaretso. Joalo ka mehla, ho bohlokoa ho buisana le mofani oa tlhokomelo ea bophelo ho fumana hore na NMN e nepahetse bakeng sa hau. Ka melemo ea eona ea bophelo bo botle le liketsahalo tsa tlhaho mefuteng eohle ea bophelo, NMN ke molek'hule eo ka sebele e tla tsoela pele ho hohela tlhokomelo ea bafuputsi le basebelisi ka ho tšoanang.
Tšebeliso ea β-nicotinamide mononucleotide e kenyelletsa:
Anti-botsofali: β-nicotinamide mononucleotide e tsebahala ka ho kenya li-sirtuin, e leng li-enzyme tse phethang karolo ea bohlokoa ho laola botsofali ba lisele. E ithutoe ka bokhoni ba eona ba ho khothaletsa tokiso ea lisele, ho ntlafatsa ts'ebetso ea mitochondrial, le ho ntlafatsa bophelo bo bolelele ka kakaretso.
Matla a metabolism: β-nicotinamide mononucleotide ke selelekela sa nicotinamide adenine dinucleotide (NAD+), coenzyme e amehang lits'ebetsong tse fapaneng tsa metabolism. Ka ho eketsa maemo a NAD+, β-nicotinamide mononucleotide e ka ts'ehetsa tlhahiso ea matla le metabolism.
Neuroprotection: Liphuputso li fana ka maikutlo a hore β-nicotinamide mononucleotide e ka ba le liphello tsa neuroprotective ka ho ntlafatsa mesebetsi ea lisele le ho sireletsa khahlanong le khatello ea oxidative le ho ruruha. E bontšitse bokhoni ba ho alafa mafu a amanang le botsofali a kang Alzheimer's le Parkinson's.
Bophelo bo botle ba pelo: β-nicotinamide mononucleotide e 'nile ea etsoa lipatlisiso bakeng sa bokhoni ba eona ba ho ntlafatsa bophelo bo botle ba pelo. E ka thusa ho sireletsa khahlanong le khatello ea oxidative, ho ruruha le ho senyeha ha methapo ea mali, ka hona ho fokotsa kotsi ea mafu a pelo.
Boikoetliso ba boikoetliso: Liphuputso tse ling li fana ka maikutlo a hore β-nicotinamide mononucleotide e ka ntlafatsa ts'ebetso ea boikoetliso le mamello ka ho ntlafatsa ts'ebetso ea mitochondrial le tlhahiso ea matla.
Nako ea poso: Jul-04-2023
