Tartaric acid, eo hape e tsejoang e le 'kojic acid' kapa 'kojic acid', ke sehlahisoa se belisoang sa likokoana-hloko se fumanoang soy sauce, soya bean paste, ritelo ea veine, 'me e ka fumanoa lihlahisoa tse ngata tse lomositsoeng tse lomositsoeng ke Aspergillus.
Bo-rasaense ba pele ba fumane hore matsoho a basebetsi ba basali ba brewry ke a masoeu ka ho khetheha. Ka mor'a boithuto ba lihlahisoa tsa ho belisoa, ho ile ha fumanoa hore ha se feela karolo e ntle ea ho boloka bocha ba curvilinear acid. E boetse e na le phello e ntle e tšoeu le e khanyang. Esita le, letlalo la letlalo ha le tšoenyehe. Lingaka tse ngata tsa dermatologists tsa Europe le Amerika li sebelisa 2 ho 4% ea kojic acid ho phekola chloasma ho bakuli ba bona ka liphello tse ntle.
Kojic acid e ka thibela ts'ebetso ea tyrosinase mme ea emisa tlhahiso ea melanin. Kojic acid ka motsoako oa 20 μg/ml e ka thibela mosebetsi oa li-enzyme tse ngata tsa tyrosinase ka 70% -80%. Ho litlolo, ho kgothaletswa ho eketsa 0.5% -2% ea tretinoin, e ka thibelang tlhahiso ea melanin le ho finyella phello ea ho soeufala le matheba a bobebe.
Ntle le phello ea eona e tšoeu, kojic acid e na le lisebelisoa tsa mahala tsa radical scavenging le antioxidant. E ka thusa letlalo la astringent, ho khothaletsa ho bokellana ha protheine le ho tiisa letlalo. Ha e na li-antibacterial tse itseng feela, empa hape e na le matla a itseng a mongobo 'me e ka ba ea sebelisoa e le se bolokang lijo le litlolo. Asiti ea Kkojic e ka thibela ts'ebetso ea hyaluronidase, e le hore e ka thibela le ho kula.
Kojic acid, e ts'oanang le VC, e tlama li-ion tsa koporo mme e etsa hore tyrosinase e sebetse.
Kojic acid e boetse e thibela tlhahiso ea melanin oxidation intermediates. Kojic acid e na le oxidised ke dopaquinone e bohareng, kahoo e fokotsa substrate ea ketane le ho thibela phetoho ea melanin bohareng ho tloha foromo ea dopaquinone ho ea ho melanin ea ho qetela. Likhakanyo tse tlase li khona ho fumana litholoana tse ntle bakeng sa phello ea eona e mabifi . Hape ke hobane phello ea eona e thata haholo e ka lebisang ho khubelu ea letlalo le ho kopana le dermatitis. Ka lebaka leo, ke ka lebaka leo lihlahisoa tse ngata tse tšoeu li nang le litlatsetso tse tlase.
Melemo ea kojic acid ke ho monya ho hoholo hoa transdermal, inhibition e ntle ea tyrosinase ebile ha e na phello ea cytotoxic. E ka sebelisoa bakeng sa ho soeufala, ho tlosa sekoli, ho ntlafatsa letlalo la letlalo, joalo-joalo; hape e ka thusa ho boloka metsi le ho eketsa elasticity ea letlalo.
Ha u sebelisa kojic acid, ho molemo ho ela hloko lintlha tse latelang.
Ntlha ea pele, kojic acid e tla hlōleha ka leseli le khanyang kapa tikoloho e matla ea acidic 'me ho e-na le hoo e eketse melanin.Ka hona, ho kgothaletswa hore lihlahisoa tsa kojic acid li sebelisoe hantle bosiu li le mong.
Ntlha ea bobeli, ho qoba tšebeliso ea salicylic acid, litholoana tsa acid, mahloriso a phahameng a VC le lisebelisoa tse ling. Ho bonolo ho feta ho susumetsa letlalo le ho phutha le ho senya mokoallo ka stacking metsoako e matla ho feta hore ho feta irritating.Tharo, lokela ho etsa matla hydration, ela hloko sunscreen ho thibela-ba khahlanong le batsho.
Le hoja kojic acid e le ace lesobeng la lefatše le soeufalang, e lokela ho sebelisoa ka hloko le ho sebelisoa ka nepo e le hore e ka phetha karolo ea bohlokoa.
Nako ea poso: Jun-08-2024
