Wholesale High Quality 4-Aminobutyric Acid Gaba Powder CAS 56-12-2

Short Description:

4-Aminobutyric acid, also known as gamma-aminobutyric acid or GABA, is an important neurotransmitter in the central nervous system of mammals. Here is an introduction to it:

Chemical Structure and Properties

• Molecular Formula and Structure: The molecular formula of 4-Aminobutyric acid is C₄H₉NO₂. Structurally, it is a four-carbon amino acid with an amino group (-NH₂) at one end and a carboxyl group (-COOH) at the other end, and the amino group is attached to the gamma-carbon atom relative to the carboxyl group.

• Solubility and Stability: It is soluble in water and has good stability under normal physiological conditions. However, it may be affected by factors such as pH and temperature, and its activity and stability need to be maintained within a certain physiological range.

Send email to us

Product Detail

Product Tags

Product Function

• Inhibitory Neurotransmission：As the primary inhibitory neurotransmitter in the central nervous system, GABA binds to GABA receptors on the postsynaptic membrane of neurons. This binding increases the permeability of the membrane to chloride ions, leading to hyperpolarization of the membrane potential and inhibiting neuronal excitability. It helps balance the excitatory and inhibitory activities in the nervous system, preventing overexcitation of neurons and maintaining the stability of neural circuits.

• Anxiolytic and Relaxant Effects：It has a significant impact on mood regulation and stress response. By inhibiting the activity of certain neurons in the limbic system and hypothalamus, GABA can reduce anxiety and promote a state of relaxation. This is why it is involved in the body's natural stress-coping mechanisms and helps individuals manage stress and anxiety.

• Sleep Regulation：GABA plays a crucial role in the regulation of the sleep-wake cycle. It inhibits the activity of arousal-promoting neurons in the brainstem and hypothalamus, facilitating the transition from wakefulness to sleep and promoting deep and restful sleep.

Application

• Pharmaceutical Industry：Many drugs that target GABA receptors or modulate GABAergic neurotransmission have been developed to treat neurological and psychiatric disorders. Benzodiazepines, for example, enhance the effect of GABA at its receptors and are commonly used as anxiolytics, sedatives, and hypnotics. Another class of drugs, barbiturates, also act on GABA receptors to produce sedative and anesthetic effects, although their use is more restricted due to potential side effects and abuse liability.

• Food and Nutritional Supplements：GABA is also used as a dietary supplement. Some people take GABA supplements to help relieve stress, improve sleep quality, and enhance mood. It is believed to have a natural calming effect and may be beneficial for individuals with mild stress or sleep problems.

• Cosmetics：In the field of cosmetics, GABA is sometimes added to skincare products. It is claimed to have muscle relaxant properties that can help reduce the appearance of fine lines and wrinkles by relaxing facial muscles.