Umsebenzi weMveliso
I-Urolithin A inemisebenzi emininzi enokwenzeka. Iyaziwa ngokukwazi kwayo ukuxhasa impilo ye-mitochondrial. Ngokuphucula umsebenzi we-mitochondrial, kunokuba negalelo ekwandiseni imveliso yamandla kwiiseli. Ikwabonisa iipropathi ze-antioxidant, ezinceda ukukhusela iiseli kumonakalo we-oxidative. Ukongeza, uphando lucebisa ukuba i-Urolithin A inokuba neziphumo ezichasayo, ezinokuba luncedo kwimpilo yonke. Ngaphezu koko, iphandwa ngendima yayo enokwenzeka ekukhuthazeni impilo yemisipha kunye nokuphucula ukusebenza komthambo. Ngokubanzi, i-Urolithin A ibambe isithembiso njengekhompawundi eneziphumo ezininzi eziluncedo kwimpilo yabantu.
Isicelo
I-Urolithin A inezicelo ezininzi:
• Ukuchasa ukuguga: Kubonise amandla kwiinkalo ezahlukeneyo zokuchasa ukuguga. Kwizilwanyana kunye nezilingo zeklinikhi, kufunyenwe ukuphucula umsebenzi we-musculoskeletal ezinxulumene neminyaka. Inokuthi isebenze kumanqanaba ahlukeneyo kunye neentlobo, ezinjengokwandisa ubomi bezinto eziphilayo ezifana ne-Caenorhabditis elegans, kwaye ibe nemiphumo emihle eluswini, ingqondo, kunye nenkqubo yomzimba yokuzikhusela yeempuku kunye nabantu. Ifezekisa iziphumo zokuchasana nokuguga ngokubangela i-mitosis, ukukhuthaza umsebenzi we-mitochondrial, kunye nokuphucula inqanaba le-metabolism yamandla omzimba.
• Ukuvuvukala kunye nokuxhatshazwa kwe-oxidation: I-Urolithin A inokuthintela ukuvuvukala kunye noxinzelelo lwe-oxidative. Inokunciphisa ukuveliswa kwezinto ezivuthayo kwaye inamandla okulwa ne-antioxidant, ukukhusela iiseli kumonakalo obangelwa yi-radicals yamahhala. Ibonisa imisebenzi ye-neuroprotective kwaye ibandakanyeka kunyango lwezifo ezahlukeneyo ezivuthayo kwizicubu ezahlukeneyo.
• Unyango lomhlaza: Uphando lubonise ukuba lunokubangela i-apoptosis kwiiseli zethumba kwaye luthintele umjikelo weseli, ngaloo ndlela luthintele i-gr.
Isatifikethi sokuHlalutya
Igama lemveliso | I-Minoxidil | MF | I-C9H15N5O |
Inombolo yeCAS. | 38304-91-5 | Umhla wokwenziwa | 2024.7.22 |
Ubungakanani | 500KG | Umhla wohlalutyo | 2024.7.29 |
Inombolo yeqela. | BF-240722 | Umhla WOKUPHELELWA | 2026.7.21 |
Izinto | Iinkcukacha | Iziphumo | |
Imbonakalo | Umgubo wekristale omhlophe okanye omhlophe | Iyahambelana | |
Ukunyibilika | Inyibilika kwipropylene glycol.inyibilika kancinane kwimethanol.Inyibilika kancinane emanzini ngokwenyani kwaye ayinakunyibilika kwichloroform, kwi-acetone, kwi-ethyl acetate, nakwihexane | Iyahambelana | |
Intsalela kwi-Ignition | ≤0.5% | 0.05% | |
Iintsimbi ezinzima | ≤20ppm | Iyahambelana | |
Ilahleko ekomisweni | ≤0.5% | 0.10% | |
Ukungcola ngokupheleleyo | ≤1.5% | 0.18% | |
Uvavanyo(HPLC) | 97.0%~103.0% | 99.8% | |
Ugcino | Gcina kwisikhongozeli esingangeni moya, sikhuselekile ekukhanyeni. | ||
Ukuqukumbela | Isampulu Ufanelekile. |