Inxalenye ebalulekileyo yeSeli Membrane —— iArachidonic Acid

I-Arachidonic acid (AA) yi-polyunsaturated omega-6 fatty acid. Yi-asidi enamafutha abalulekileyo, okuthetha ukuba umzimba womntu awukwazi ukuyidibanisa kwaye kufuneka uyifumane ekutyeni. Iasidi yeArachidonic idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zomzimba kwaye ibaluleke kakhulu kulwakhiwo kunye nokusebenza kweenwebu zeseli.

Nazi ezinye iingongoma eziphambili malunga ne-arachidonic acid:

Imithombo:

I-Arachidonic acid ifumaneka ikakhulu kukutya okusekelwe kwizilwanyana, ngakumbi kwinyama, amaqanda, kunye neemveliso zobisi.

Inokuthi yenziwe emzimbeni ukusuka kwi-precursors yokutya, njenge-linoleic acid, enye enye i-asidi enamafutha abalulekileyo efumaneka kwioli yezityalo.

ImiSebenzi yebhayoloji:

Isakhiwo seMembrane yeCell: I-Arachidonic acid iyona nxalenye ephambili yeembrane zeseli, igalelo kwisakhiwo sabo kunye nolwelo.

Impendulo evuthayo: I-Arachidonic acid isebenza njenge-precursor ye-synthesis ye-molekyuli yokubonisa eyaziwa ngokuba yi-eicosanoids. Ezi ziquka i-prostaglandins, i-thromboxanes, kunye ne-leukotrienes, ezidlala indima ebalulekileyo kwiimpendulo zomzimba ezivuthayo kunye ne-immune.

Umsebenzi we-Neurological: I-Arachidonic acid ikhona kwiindawo eziphezulu kwingqondo kwaye ibalulekile ekuphuhliseni nasekusebenzeni kwenkqubo ye-nervous central.

Ukukhula kwemisipha kunye nokulungiswa: Ibandakanyeka kulawulo lweprotheyini ye-muscle synthesis kwaye inokudlala indima ekukhuleni kwemisipha kunye nokulungiswa.

I-Eicosanoids kunye nokudumba:

Ukuguqulwa kwe-arachidonic acid kwi-eicosanoids yinkqubo elawulwa ngokuqinileyo. I-Eicosanoids ephuma kwi-arachidonic acid ingaba nemiphumo emibi kunye ne-anti-inflammatory, kuxhomekeke kuhlobo oluthile lwe-eicosanoid kunye nomxholo oveliswayo.

Amanye amayeza achasene nokudumba, njengeziyobisi ezichasa ukudumba (i-NSAIDs), asebenza ngokuthintela ama-enzymes abandakanyekayo ekuhlanganisweni kwe-eicosanoids ethile evela kwi-arachidonic acid.

Ukuqwalaselwa kokutya:

Nangona i-arachidonic acid ibalulekile kwimpilo, ukutya okugqithisileyo kwe-omega-6 fatty acids (kubandakanywa ne-arachidonic acid precursors) ngokubhekiselele kwi-omega-3 fatty acids ekudleni kuye kwadibaniswa nokungalingani okunokuthi kube negalelo kwiimeko ezingapheliyo ezivuthayo.

Ukufezekisa umlinganiselo olungelelanisiweyo we-omega-6 ukuya kwi-omega-3 fatty acids ekudleni kudla ngokuthathwa njengento ebalulekileyo kwimpilo yonke.

Ukongeza:

Izongezelelo ze-Arachidonic acid ziyafumaneka, kodwa kubalulekile ukusondela kwi-supplementation ngononophelo, njengoko ukutya kakhulu kunokuba nefuthe lokudumba kunye nempilo iyonke. Phambi kokuba uthathele ingqalelo ukongeza, kuyacetyiswa ukuba udibane nengcali yezempilo.

Isishwankathelo, i-arachidonic acid iyinxalenye ebalulekileyo yeembrane zeseli kwaye ibandakanyeka kwiinkqubo ezahlukeneyo ze-physiological, kubandakanywa ukuvuvukala kunye neempendulo ze-immune. Nangona kubalulekile kwimpilo, ukugcina ukutya okulinganayo kwe-omega-6 kunye ne-omega-3 fatty acids kubalulekile kwimpilo jikelele. Njengalo naliphi na icandelo lokutya, iimfuno zomntu ngamnye kunye neemeko zempilo kufuneka ziqwalaselwe, kwaye iingcebiso kwiingcali zezempilo kufuneka zifunwe xa uthandabuza.