I-Methyl 4-hydroxybenzoate I-Methylparaben enye ye-parabens, i-preservative kunye ne-chemical formula CH3 (C6H4 (OH) COO). Yi-methyl ester ye-p-hydroxybenzoic acid.
I-Methyl 4-hydroxybenzoate I-Methylparaben isebenza njengepheromone kwiindidi zezinambuzane kwaye iyingxenye ye-queen mandibular pheromone.
Yipheromone kwiingcuka eziveliswa ngexesha le-estrus elinxulunyaniswa nokuziphatha kweengcuka zamadoda e-alpha ezithintela ezinye iinkunzi ekunyuseni iimazi ebushushwini.
I-Methyl 4-hydroxybenzoate I-Methylparaben yi-arhente echasene nomngundo edla ngokusetyenziswa kwiintlobo ngeentlobo zezithambiso kunye neemveliso zokhathalelo lomntu. Ikwasetyenziswa njengento egcina ukutya.
I-Methyl 4-hydroxybenzoate I-Methylparaben isetyenziswa ngokuqhelekileyo njenge-fungicide kwi-Drosophila media media kwi-0.1%. Kwi-Drosophila, i-methyl 4-hydroxybenzoate methylparaben inetyhefu kwiindawo eziphezulu, inefuthe le-estrogenic (ukulinganisa i-estrogen kwiigundane kunye nomsebenzi ochasene ne-androgenic), kwaye iyancipha izinga lokukhula kwisigaba se-larval kunye ne-pupal kwi-0.2%.
Kukho impikiswano malunga nokuba i-methyl 4-hydroxybenzoate methylparaben okanye i-propylparabens iyingozi ekugxininiseni okuqhelekileyo kusetyenziswa kukhathalelo lomzimba okanye kwizinto zokuthambisa. I-Methylparaben kunye ne-propylparaben zibonwa njengesiqhelo njengekhuselekile (GRAS) yi-USFDA yokutya kunye nokugcinwa kwe-antibacterial yokuthambisa. I-Methyl 4-hydroxybenzoate I-Methylparaben igawulwa lula yibhaktiriya yomhlaba eqhelekileyo, iyenze ibole ngokupheleleyo.
I-Methyl 4-hydroxybenzoate I-Methylparaben ifunxwa ngokulula kwiphecana lesisu okanye ngesikhumba. I-hydrolyzed ukuya kwi-p-hydroxybenzoic acid kwaye ikhutshwe ngokukhawuleza kumchamo ngaphandle kokuqokelela emzimbeni. Uphononongo olubukhali lobutyhefu lubonise ukuba i-methylparaben ayinayo ityhefu ngokulawulwa komlomo kunye nabazali kwizilwanyana. Kuluntu olunolusu oluqhelekileyo, i-methylparaben iyinto engabonakaliyo kwaye ingabonakali; nangona kunjalo, ukusabela kwe-aleji kwiiparabens ezityiweyo kuye kwabikwa. Uphononongo lwe-2008 alufumananga ukukhuphisana okubophelelayo kwi-estrogen yabantu kunye ne-androgen receptors ye-methylparaben, kodwa amanqanaba ahlukeneyo okubopha okukhuphisanayo abonwa nge-butyl- kunye ne-isobutyl-paraben.
Uphononongo lubonisa ukuba i-methylparaben esetyenzisiweyo eluswini inokusabela nge-UVB, ekhokelela ekwandiseni ukuguga kwesikhumba kunye nomonakalo weDNA.
Ukuphendula kwezi nkxalabo, ezinye ii-arhente ezilawulayo kunye nemibutho ziye zathatha amanyathelo okuthintela ukusetyenziswa kwe-methyl paraben kwiimveliso ezithile. Ngokomzekelo, i-European Union iyanciphisa ukuxinwa kwe-methyl paraben evunyelwe kwizinto zokuthambisa, kwaye abanye abavelisi bakhethe ukuhlaziya iimveliso zabo ukuba zingabi ne-paraben. Ukongezelela, ukukhula kweemfuno zendalo kunye neendlela ezizezinye zezinto eziphilayo eziye zakhokelela ekuphuhlisweni kweendlela ezintsha ezingenayo i-methyl paraben okanye ezinye iiparabens.
I-Methylparaben ithandwa ngenxa yokuzinza kunye nokuhambelana neentlobo ezahlukeneyo zokuqulunqa. Ngokwesiqhelo ayiwuguquli umbala, ivumba, okanye ukumila kweemveliso ezisetyenzisiweyo, nto leyo eyenza ukuba ibe sisithako esisebenza ngeendlela ezininzi kumenzi. Olu uzinzo lwandisa ubomi beshelufu kwaye lunceda ukugcina umgangatho uwonke wemveliso kwixesha elide.
Abathengi kufuneka baqonde iimvakalelo zabo zobuqu kunye nezinto ezinokuthi zibe khona xa besebenzisa iimveliso ezine-methylparaben. Nangona i-methylparaben ngokuqhelekileyo ithathwa njengekhuselekile ukusetyenziswa kwizithambiso, abanye abantu banokufumana ukucaphuka kwesikhumba okanye ukuphazamiseka. Kuhlala kucetyiswa ukuba wenze uvavanyo lwe-patch phambi kokusebenzisa imveliso entsha ukubona ukuba kukho naziphi na iziphumo ezibi.
Ukuqukumbela, i-methyl 4-hydroxybenzoate okanye i-methylparaben yinto esetyenziswa ngokubanzi kwi-cosmetic kunye ne-pharmaceutical industry. Nangona impikiswano ngenxa yokukhathazeka malunga nemiphumo enokubakho kumanqanaba ehomoni kunye nempilo yokuzala, ihlala ithandwa kakhulu ekugcinweni kwemveliso ngenxa yokusebenza kwayo, ukuzinza, kunye nokuhambelana neendlela ezahlukeneyo zokuqulunqa. Njengoko imfuno yemveliso yendalo kunye ne-organic iqhubeka ikhula, ukusetyenziswa kwe-methylparaben kunokwenzeka ukuba kuguquke kwaye ezinye izilondolozo zinokuxhaphaka kakhulu kwimarike. Abathengi kufuneka baqonde izithako kwiimveliso abazisebenzisayo kwaye benze ukhetho oluhambelana nezinto abazithandayo kunye neenkxalabo zabo.
Ixesha lokuposa: Apr-19-2024
