I-Antioxidant yeNdalo eKhuselekileyo kakhulu kunye ne-Non-toxic yeSeli: i-Ergothioneine

I-Ergothioneine yi-antioxidant yendalo enokukhusela iiseli emzimbeni womntu kwaye yinto ebalulekileyo esebenzayo kwizinto eziphilayo. I-antioxidants yendalo ikhuselekile kwaye ayinayo ityhefu kwaye ibe yindawo yophando. I-Ergothioneine ingene kwintsimi yombono yabantu njenge-antioxidant yendalo. Inemisebenzi eyahlukeneyo yomzimba enjengokukhupha iiradicals zasimahla, ukukhupha ubuthi, ukugcina iDNA biosynthesis, ukukhula kweeseli okuqhelekileyo kunye nokunganyangeki kweselula.

Ngenxa yemisebenzi ebalulekileyo neyodwa yebhayoloji ye-ergothioneine, abaphengululi abavela kumazwe ahlukeneyo bebefunda indlela esetyenziswa ngayo ixesha elide. Nangona isafuna uphuhliso olongezelelweyo, inenkuthazo enkulu ekusebenziseni kwayo kwiinkalo ezahlukeneyo. I-Ergothioneine inesicelo esibanzi kunye nethemba lokuthengisa kwiinkalo zokutshintshwa kwamalungu, ukugcinwa kweeseli, amayeza, ukutya kunye neziphuzo, ukutya okusebenzayo, ukutya kwezilwanyana, izimonyo kunye ne-biotechnology.

Nazi ezinye izicelo ze-ergothioneine:

Isebenza njenge-antioxidant ekhethekileyo

I-Ergothioneine sisisithinteli esikhusela iiseli kakhulu, esingenatyhefu yendalo yokulwa ne-antioxidant engafakwanga lula emanzini, siyivumela ukuba ifikelele kugxininiso oluya kuthi ga kwi-mmol kwezinye izihlunu kwaye ivuselele inkqubo yokhuselo yendalo yeeseli. Phakathi kwee-antioxidants ezininzi ezikhoyo, i-ergothioneine ihluke ngokukodwa kuba i-chelates i-ion yensimbi enzima, ngaloo ndlela ikhusela iiseli ezibomvu zegazi emzimbeni kumonakalo omkhulu wamahhala.

Ufakelo lwamalungu

Ubungakanani kunye nobude bexesha lokugcinwa kwezicubu ezikhoyo zidlala indima ebalulekileyo kwimpumelelo yokutshintshwa kwamalungu. Eyona nto isetyenziswa ngokuqhelekileyo i-antioxidant ekugcinweni kwamalungu yi-glutathione, ene-oxidized kakhulu xa ibonakaliswe kwindalo. Nakwindawo efrijini okanye elulwelo, amandla ayo okulwa ne-antioxidant ancitshiswa kakhulu, abangela i-cytotoxicity kunye nokudumba, kunye ne-proteolysis yezicubu. I-Ergothioneine ibonakala ngathi i-antioxidant ezinzileyo kwisisombululo esinamanzi kwaye iyakwazi ukutshisa i-ion zensimbi ezinzima. Ingasetyenziselwa indawo ye-glutathione kwintsimi yokukhusela amalungu ukukhusela ngcono izitho ezitshintshiweyo.

Yongezwa kwizinto zokuthambisa njengesikhuseli solusu

Imitha ye-UVA ye-UVA elangeni inokungena kwi-dermis layer yolusu lomntu, ichaphazela ukukhula kweeseli ze-epidermal, ibangele ukufa kweeseli ezingaphezulu, okukhokelela ekugugeni kwangaphambi kwexesha, ngelixa imitha ye-ultraviolet UVB inokubangela umhlaza wolusu ngokulula. I-Ergothioneine inokunciphisa ukwakheka kweentlobo zeoksijini esebenzayo kwaye ikhusele iiseli kumonakalo wemitha, ngoko ke i-ergothioneine inokongezwa kwezinye izinto zokuthambisa njengesikhuseli solusu kuphuhliso lweemveliso zokhathalelo lwesikhumba lwangaphandle kunye nezithambiso ezikhuselayo.

Ukusetyenziswa kwamehlo

Kwiminyaka yakutshanje, kuye kwafunyaniswa ukuba i-ergothioneine idlala indima ebalulekileyo ekukhuselweni kwamehlo, kwaye abaphandi abaninzi banethemba lokuphuhlisa imveliso ye-ophthalmic ukuququzelela utyando lwamehlo lonyango. Utyando lwamehlo luqhele ukwenziwa ekuhlaleni. Ukunyibilika kwamanzi kunye nokuzinza kwe-ergothioneine kubonelela ngokunokwenzeka kotyando olunjalo kwaye lunexabiso elikhulu lesicelo.

Ukusetyenziswa kweminye imimandla

I-Ergothioneine isetyenziswa kwiinkalo ezininzi ngenxa yeempawu zayo ezintle. Ngokomzekelo, isetyenziswe kwintsimi yamachiza, intsimi yokutya, intsimi yokunakekelwa kwempilo, intsimi yezimonyo, njl. Kwintsimi yeyeza, ingasetyenziselwa ukunyanga ukuvuvukala, njl., kwaye ingenziwa kwiipilisi, iipilisi, ngomlomo. amalungiselelo, njl.; Kwintsimi yeemveliso zempilo, inokuthintela ukuvela komhlaza, njl., kwaye inokwenziwa kukutya okusebenzayo, iziphuzo ezisebenzayo, njl.; Kwintsimi yezinto zokuthambisa, ingasetyenziselwa Isetyenziselwa ukuchasana nokuguga kwaye ingenziwa kwi-sunscreen kunye nezinye iimveliso.

Njengoko ulwazi lwabantu ngokhathalelo lwempilo lusanda, iipropathi ezibalaseleyo ze-ergothioneine njenge-antioxidant yendalo ziya kuthi ngokuthe ngcembe ziqondwe ngokubanzi kwaye zisetyenziswe.