Isizukulwana sesithathu seCarnosine Derivatives:N-acetyl carnosine

Kwimbali yase China, indlwane yeentaka ithathwa njenge tonic, eyaziwa ngokuba yi "Oriental Caviar". Kurekhodwe kwi-Materia Medica ukuba indlwane yeentaka “yithoni kwaye inokucocwa, kwaye liyeza elingcwele lokulawula ukunqongophala nokusebenza”. I-N-Acetyl Neuraminic Acid sesona sithako siphambili kwindlwane yeentaka, ngoko ikwabizwa ngokuba yi-bird's nest acid, kwaye umxholo wayo ukwaluphawu lomgangatho wentaka.

I-N-acetyl carnosine (NAC) yinto eyenzeka ngokwemvelo yekhemikhali ehambelana ne-dipeptide carnosine.Isakhiwo se-molecular ye-NAC ifana ne-carnosine ngaphandle kokuba ithwala iqela le-acetyl elongezelelweyo. I-Acetylation yenza i-NAC ixhathise ngakumbi ukuthotywa kwe-myostatin, i-enzyme ephula i-myostatin kwi-amino acids edibeneyo i-β-alanine kunye ne-histidine.

I-O-Acetyl Carnosine yinto eyenziwa ngokwemvelo ye-carnosine derivative eyaqala ukuchongwa kwi-muscle muscle ye-rabbit ngo-1975. Kubantu, i-acetyl carnosine ifumaneka ngokuyinhloko kwi-skeletal muscle, kwaye izicubu ze-muscle zikhupha icandelo xa umntu eqhuba.

Njengoko isizukulwana sesithathu se-carnosine derivatives yendalo, i-acetyl carnosine inamandla anamandla onke, ukuguqulwa kwe-acetylation kwenza ukuba kungabonakali kwaye kuthotywe yi-carnosine peptidase emzimbeni womntu, kwaye kunozinzo oluphezulu.Zineziphumo ezicacileyo kwi-antioxidant, i-anti-glycation , anti-ukudumba, njl.

I-Acetyl carnosine ayiphuculi kakhulu kuphela ukuzinza, kodwa iphinda izuze i-antioxidant kunye ne-anti-inflammatory effects of carnosine.

I-Acetyl carnosine ineempembelelo ezininzi, ayinakudlala kuphela ukuqina, ukuthoba, ukuthambisa kunye nezinye iziphumo zokunakekelwa kwesikhumba, kodwa kwakhona inqanda isizukulwana se-oxygen esebenzayo i-radicals yamahhala, izinto ezivuthayo, isetyenziswe ngokubanzi kunyango lweempawu ze-cataract zamaconsi esweni.

I-Acetyl carnosine iphinda isetyenziswe kwezinye izimonyo okanye iimveliso zokunyamekela.Ngokomzekelo, iimveliso zokunakekelwa kwesikhumba ebusweni, umzimba, intamo, izandla, kunye nesikhumba seperiocular; iimveliso zobuhle kunye nenkathalo (umz., iiloshini, iikhrimu ze-AM/PM, iiserum); i-antioxidants, i-skin conditioners, okanye i-moisturizers kwi-cosmetics kunye neemveliso ze-skincare; kunye nezixhasi zokuphilisa kwizithambiso.

Ukushwankathela, njengezinto ezenzeka ngokwemvelo emzimbeni womntu, i-myostatin kunye ne-derivatives yayo inezinga eliphezulu kakhulu lokhuseleko.