IVithamin B1 -- IiCofactors of Human Energy Metabolism

I-Vitamin B1, ekwabizwa ngokuba yi-thiamine, yivithamin enyibilikayo emanzini edlala indima ebalulekileyo kwimetabolism yeecarbohydrates. Nazi iingongoma eziphambili malunga ne-vitamin B1:
Ulwakhiwo lweMichiza:
I-Thiamine yi-vitamin ye-B e-soluble yamanzi ene-chemical structure equka i-thiazole kunye ne-pyrimidine ring. Ikhona kwiifom ezininzi, kunye ne-thiamine pyrophosphate (TPP) ibe yifom ye-coenzyme esebenzayo.
Umsebenzi:
I-Thiamine ibalulekile ekuguquleni iicarbohydrates zibe ngamandla. Isebenza njenge-coenzyme kwiimpendulo ezininzi ezibalulekileyo ze-biochemical ezibandakanyekayo ekuqhekekeni kweglucose.
Idlala indima ebalulekileyo ekusebenzeni kweeseli ze-nerve kwaye ibalulekile ekusebenzeni ngokufanelekileyo kwenkqubo ye-nervous.
Imithombo:
Imithombo efanelekileyo yokutya ye-thiamine iquka iinkozo ezipheleleyo, iisiriyeli eziqinisiweyo, iimbotyi (ezifana neembotyi kunye nelentile), amandongomane, imbewu, inyama yehagu kunye negwele.
Ukunqongophala:
Ukunqongophala kweThiamine kunokukhokelela kwimeko eyaziwa ngokuba yi-beriberi. Kukho iintlobo ezimbini eziphambili ze-beriberi:
I-Beriberi emanzi:Ibandakanya iimpawu ze-cardiovascular kwaye kunokukhokelela ekuphelelweni kwentliziyo.
I-Beriberi eyomileyo:Ichaphazela inkqubo ye-nervous, ekhokelela kwiimpawu ezifana nobuthakathaka bemisipha, ukubetha, kunye nobunzima bokuhamba.
Ukunqongophala kwe-Thiamine kunokwenzeka nakubantu abatya ukutya okuphezulu kwi-carbohydrate esulungekileyo kunye nokutya okuphantsi kwe-thiamine.
Iimeko ezinxulumene nokunqongophala kweThiamine:
Ukukhotyokiswa butywala okungapheliyo kungunobangela oqhelekileyo wokunqongophala kwethiamine. Imeko yaziwa ngokuba yi-Wernicke-Korsakoff syndrome, kwaye inokukhokelela kwiimpawu ezinzima ze-neurological.
Iimeko ezichaphazela ukufunxa izondlo, ezifana nesifo sikaCrohn okanye utyando lwe-bariatric, kunokunyusa umngcipheko wokunqongophala kwe-thiamine.
ISibonelelo seMihla esicetyiswayo (RDA):
Umthamo ocetyiswayo wemihla ngemihla we-thiamine uyahluka ngokweminyaka, isini, kunye nenqanaba lobomi. Ibonakaliswa ngeemilligrams.
Ukongeza:
I-Thiamine supplementation idla ngokucetyiswa kwiimeko zokunqongophala okanye xa kukho imfuneko eyongeziweyo, njengaxa ukhulelwe okanye uncancisa. Ngamanye amaxesha ikwamiselwa abantu abaneemeko ezithile zonyango.
Ubuzaza Bobushushu:
I-Thiamine ivakalelwa kubushushu. Ukupheka kunye nokulungiswa kunokukhokelela ekulahlekeni kwe-thiamine ekutyeni. Ke ngoko, kubalulekile ukubandakanya iintlobo ezahlukeneyo zokutya okutsha kunye nokucutshungulwa kancinci ekutyeni ukuqinisekisa ukutya okwaneleyo.
Ukudibana namayeza:
Amanye amayeza, afana ne-diuretics kunye namayeza okulwa nokuxhuzula, anokunyusa imfuno yomzimba ye-thiamine. Kubalulekile ukubonisana nengcali yezempilo ukuba kukho iinkxalabo malunga nemeko ye-thiamine, ngakumbi kwimeko yokusetyenziswa kwamayeza.
Ukuqinisekisa ukutya okwaneleyo kwe-thiamine ngokutya okunokulinganisela kubalulekile kwimpilo yonke, ngakumbi ekusebenzeni kakuhle kwenkqubo ye-nervous kunye ne-metabolism yamandla. Ukuba kukho iinkxalabo malunga nokunqongophala kwe-thiamine okanye ukongezwa, kuyacetyiswa ukuba udibane nengcali yezempilo ukuze ufumane isikhokelo somntu.