Intshayelelo yeMveliso
I-Thiamidol sisithako se-anti-pigment esinelungelo elilodwa lomenzi wechiza elaphuhliswa emva kweminyaka engaphezu kweshumi yophando. Esi sithako esisebenzayo siphawula ukuguquka kophando ekususweni kwendawo ye-pigment - isiphumo se-thiamidol sijoliswe kwaye sibuyiselwa umva, ngoko ke iimveliso zibonakaliswe ukuba zisebenza kwaye zikhuselekile. Ngaphambi kolu phando, kwakungenakwenzeka ukuphuhlisa isithako esisebenzayo esisebenza ngokuchanekileyo. Ngokuchasene noko, kude kube ngoko kwakunokwenzeka kuphela ukuthintela ukusasazwa ngomzekelo, i-niacianamides kunye nezinye izithako ezisebenzayo. I-Niacianamide iyodwa ayiyo-inhibitor ye-tyrosine yabantu kwaye iphazamisa kuphela ukuhanjiswa kwe-melanin.
Umsebenzi
Isiphumo esimhlophe seThiamidol sibaluleke kakhulu:
1. Ukuvinjelwa komsebenzi we-tyrosinase yabantu: I-Thiamidol yenye yezona zinto zinamandla zokuthintela umsebenzi we-tyrosinase owaziwayo ngoku, onokuthi uthintele ukubunjwa kwe-melanin kumthombo.
2. Ikhuselekile kwaye imnene: I-Thiamidol ayinayo i-cytotoxicity kwaye iyisithako esimhlophe esikhuselekileyo nesithambileyo. I-Thiamidol ineenzuzo ezinkulu ngaphezu kwezinye izithako ezimhlophe.
3. Ukusebenza kakuhle: I-Thiamidol inokuphucula ngokufanelekileyo i-melasma epholileyo, ephakathi kunye nenzima, kwaye inokuphucula ngokufanelekileyo amabala e-pigmentation kunye neendawo zobudala.
Isatifikethi sokuHlalutya
Igama lemveliso | Thiamidol | Inkcazo | Umgangatho weNkampani |
CASHayi. | 1428450-95-6 | Umhla wokwenziwa | 2024.7.20 |
Ubungakanani | 100KG | Umhla wohlalutyo | 2024.7.27 |
Inombolo yeqela. | ES-240720 | Umhla WOKUPHELELWA | 2026.7.19 |
Ubunzima bemolekyuli | 278.33 | Isimboli semolekyuli | C₁₈H₂₃NO₃S |
Izinto | Iinkcukacha | Iziphumo | |
Imbonakalo | Umgubo omhlophe ukuya kumhlophe | Iyahambelana | |
Ukuchongwa | Ixesha lokugcinwa kwencopho enkulu yesisombululo sesampulu sihambelana nesisombululo esiqhelekileyo | Iyahambelana | |
Isiqulatho samanzi | ≤1.0% | 0.20% | |
Intsalela yesinyibilikisi (GC) | I-acetonitrile≤0.041% | ND | |
| Dichloromethane≤0.06% | ND | |
| iToluene≤0.089% | ND | |
| Heptane≤0.5% | 60ppm | |
| I-Ethanol≤0.5% | ND | |
| I-Ethyl acetate≤0.5% | 1319ppm | |
| Iacetic acid≤0.5% | ND | |
Izinto eziyeleleneyo (HPLC) | Ukungacoceki okukodwa≤1.0% | 0.27% | |
| Iyonke Impuritics≤2.0% | 0.44% | |
Intsalela kwi-Ignition | ≤0.5% | 0.03% | |
Isivavanyi(HPLC) | 98.0%~102.0% | 98.5% | |
Ugcino | Gcina kwisikhongozeli esiqinile emoyeni, esikhuselwe ekukhanyeni. | ||
Beka ubomi kwishelufa | Iminyaka emibini xa igcinwe ngokufanelekileyo. | ||
Ukuqukumbela | Ufanelekile. |
Uhlolo lwabasebenzi: Yan Li Phonononga abasebenzi: Lifen Zhang abasebenzi abagunyazisiweyo: LeiLiu