Umsebenzi Wokukhiqiza
I-Urolithin A inemisebenzi eminingi engaba khona. Yaziwa ngamandla ayo okusekela impilo ye-mitochondrial. Ngokuthuthukisa ukusebenza kwe-mitochondrial, kungaba nomthelela ekwandeni kokukhiqizwa kwamandla kumaseli. Ibuye ibonise izakhiwo ze-antioxidant, ezisiza ukuvikela amangqamuzana emonakalweni we-oxidative. Ukwengeza, ucwaningo lubonisa ukuthi i-Urolithin A ingase ibe nemiphumela elwa nokuvuvukala, engaba nenzuzo empilweni yonke. Ngaphezu kwalokho, kuphenywa ngeqhaza layo elingenzeka ekukhuthazeni impilo yemisipha kanye nokwenza ngcono ukusebenza kokuzivocavoca. Sekukonke, i-Urolithin A inesithembiso njengenhlanganisela enemiphumela eminingi enenzuzo empilweni yomuntu.
Isicelo
I-Urolithin A inezinhlelo zokusebenza ezimbalwa:
• Ukuvimbela ukuguga: Kubonise amandla ezicini ezihlukahlukene zokulwa nokuguga. Ezivivinyweni zezilwane nezomtholampilo, kutholakale ukuthi kuthuthukisa umsebenzi we-musculoskeletal ohlobene neminyaka. Ingasebenza kumazinga ahlukene kanye nezinhlobo zezinto eziphilayo, njengokwelula isikhathi sokuphila kwezinto eziphilayo ezifana ne-Caenorhabditis elegans, futhi ibe nemiphumela emihle esikhumbeni, ebuchosheni, namasosha omzimba wamagundane nabantu. Ifinyelela imiphumela yokulwa nokuguga ngokwenza i-mitosis, ikhuthaze ukusebenza kwe-mitochondrial, futhi ithuthukise izinga lomzimba wamandla we-metabolism.
• Ukuvuvukala nokumelana ne-oxidation: I-Urolithin A ingavimbela ukuvuvukala nokucindezeleka okwenziwe nge-oxidative. Inganciphisa ukukhiqizwa kwezinto ezivuvukalayo futhi inamandla e-antioxidant, ivikela amangqamuzana emonakalweni obangelwa ama-radicals mahhala. Ibonisa imisebenzi ye-neuroprotective futhi ihileleke ekwelapheni izifo ezihlukahlukene zokuvuvukala ezicutshini ezahlukene.
• Ukwelashwa komdlavuza: Ucwaningo lubonise ukuthi lungabangela i-apoptosis kumaseli wesimila futhi luvimbele umjikelezo weseli, ngaleyo ndlela luvimbele i-gr.
Isitifiketi Sokuhlaziya
Igama Lomkhiqizo | I-Minoxidil | MF | I-C9H15N5O |
Inombolo ye-CAS. | 38304-91-5 | Usuku Lokukhiqiza | 2024.7.22 |
Ubuningi | 500KG | Idethi yokuhlaziya | 2024.7.29 |
Inombolo yeqoqo. | I-BF-240722 | Usuku Eliphelela ngalo | 2026.7.21 |
Izinto | Imininingwane | Imiphumela | |
Ukubukeka | I-crystal powder emhlophe noma emhlophe | Iyahambisana | |
Ukuncibilika | Incibilika ku-propylene glycol.incibilika kancane ku-methanol.incibilika kancane emanzini cishe ayincibiliki ku-chloroform, ku-acetone, ku-ethyl acetate, naku-hexane | Iyahambisana | |
I-Residue Ekushiseni | ≤0.5% | 0.05% | |
Izinsimbi Ezisindayo | ≤20ppm | Iyahambisana | |
Ukulahlekelwa Ekumisweni | ≤0.5% | 0.10% | |
Ukungcola Okuphelele | ≤1.5% | 0.18% | |
I-Assay(HPLC) | 97.0%~103.0% | 99.8% | |
Isitoreji | Gcina esitsheni esingangeni moya, esivikelwe ekukhanyeni. | ||
Isiphetho | Isampula Lifanelekile. |