I-Factory Supply Succinic Acid Amber Acid Cas 110-15-6

I-Succinic acid i-dicarboxylic acid enefomula yamakhemikhali (CH2)2(CO2H)2.Igama lisuselwa ku-Latin succinum, okusho inhlaka. Ezintweni eziphilayo, i-succinic acid ithatha isimo se-anion, i-succinate, enezindima eziningi zebhayoloji njengengxenye ye-metabolic eguqulwa ibe yi-fumarate yi-enzyme succinate dehydrogenase ku-complex 2 yeketango lezokuthutha lama-electron elihilelekile ekwenzeni i-ATP, futhi i-molecule ebonisa isimo se-metabolic yeselula. I-Succinate ikhiqizwa ku-mitochondria ngomjikelezo we-tricarboxylic acid (TCA), inqubo ekhiqiza amandla ehlanganyelwa yizo zonke izinto eziphilayo. I-Succinate ingaphuma ku-matrix ye-mitochondrial futhi isebenze ku-cytoplasm kanye nesikhala esingaphandle kwamangqamuzana, iguqule amaphethini wokuvezwa kwezakhi zofuzo, ilungise isimo se-epigenetic noma ibonise ukusayinda okufana nehomoni. Kanjalo, i-succinate ixhumanisa i-metabolism yamaselula, ikakhulukazi ukwakheka kwe-ATP, nokulawulwa kokusebenza kwamaselula. I-Dysregulation of succinate synthesis, ngakho-ke i-ATP synthesis, kwenzeka kwezinye izifo ze-mitochondrial zofuzo, njenge-Leigh syndrome, ne-Melas syndrome, futhi ukuwohloka kungaholela ezimweni ze-pathological, njengokuguquka okulimazayo, ukuvuvukala nokulimala kwezicubu.