I-Antioxidant Yemvelo Evikela Kakhulu Nengenabo Ubuthi Yamaseli: I-Ergothioneine

I-Ergothioneine iyi-antioxidant yemvelo engavikela amaseli emzimbeni womuntu futhi iyinto ebalulekile esebenzayo ezintweni eziphilayo. Ama-antioxidants emvelo aphephile futhi awanabo ubuthi futhi asephenduke indawo yocwaningo. I-Ergothioneine ingene emkhakheni wombono wabantu njenge-antioxidant yemvelo. Inemisebenzi ehlukahlukene yezemvelo efana nokukhipha ama-radicals mahhala, ukukhipha ubuthi, ukugcina i-DNA biosynthesis, ukukhula kwamangqamuzana okuvamile kanye nokuzivikela komzimba kwamaselula.

Ngenxa yemisebenzi yebhayoloji ebalulekile neyingqayizivele ye-ergothioneine, izazi ezivela emazweni ahlukahlukene bezilokhu zifunda ukusetshenziswa kwayo isikhathi eside. Yize isadinga ukuthuthukiswa, inogqozi olukhulu ekusetshenzisweni kwayo emikhakheni eyahlukene. I-Ergothioneine inezinhlelo ezibanzi zokusebenzisa kanye namathemba emakethe emkhakheni wokufakelwa izitho zomzimba, ukulondolozwa kwamaseli, umuthi, ukudla neziphuzo, ukudla okusebenzayo, ukudla kwezilwane, izimonyo kanye ne-biotechnology.

Nazi ezinye izinhlelo zokusebenza ze-ergothioneine:

Isebenza njenge-antioxidant eyingqayizivele

I-Ergothioneine iyi-antioxidant evikela amangqamuzana kakhulu, engenabuthi engafakwa kalula emanzini, eyivumela ukuthi ifinyelele ekugxilweni okufika ku-mmol kwezinye izicubu futhi ikhuthaze isimiso sokuzivikela semvelo samaseli. Phakathi kwama-antioxidants amaningi atholakalayo, i-ergothioneine iyingqayizivele ikakhulukazi ngoba i-chelates ama-ion ensimbi, ngaleyo ndlela ivikela amangqamuzana egazi abomvu emzimbeni ekulimaleni kwama-radical mahhala.

Ukufakelwa izitho zomzimba

Inani kanye nobude besikhathi sokulondolozwa kwezicubu ezikhona zidlala indima ebalulekile empumelelweni yokufakelwa kwezitho zomzimba. I-antioxidant esetshenziswa kakhulu ekulondolozweni kwezitho yi-glutathione, ekhishwa nge-oxidized kakhulu lapho ivezwe endaweni ezungezile. Ngisho nasezindaweni eziqandisiwe noma eziwuketshezi, amandla ayo okulwa ne-antioxidant ancipha kakhulu, okubangela i-cytotoxicity nokuvuvukala, futhi kubangele izicubu ze-proteolysis. I-Ergothioneine ibonakala iyi-antioxidant ezinzile kwisisombululo esinamanzi futhi ingaphinda ihlaziye ama-ion ensimbi. Ingasetshenziswa esikhundleni se-glutathione emkhakheni wokuvikelwa kwezitho ukuze kuvikelwe kangcono izitho ezitshaliwe.

Kwengezwe kuzimonyo njengesivikelo sesikhumba

Imisebe ye-UVA ye-UVA elangeni ingangena ongqimbeni lwesikhumba somuntu, ithinte ukukhula kwamangqamuzana e-epidermal, ibangele ukufa kwamangqamuzana angaphezulu, okuholela ekugugeni kwesikhumba ngaphambi kwesikhathi, kuyilapho imisebe ye-ultraviolet UVB ingabangela kalula umdlavuza wesikhumba. I-Ergothioneine inganciphisa ukwakheka kwezinhlobo zomoya-mpilo osebenzayo futhi ivikele amangqamuzana emonakalweni wemisebe, ngakho-ke i-ergothioneine ingangezwa kwezinye izimonyo njengesivikelo sesikhumba sokuthuthukiswa kwemikhiqizo yokunakekelwa kwesikhumba yangaphandle kanye nezimonyo ezivikelayo.

Izicelo ze-Ophthalmic

Eminyakeni yamuva nje, kutholakale ukuthi i-ergothioneine idlala indima ebalulekile ekuvikelweni kwamehlo, futhi abacwaningi abaningi banethemba lokuthuthukisa umkhiqizo wamehlo ukuze kube lula ukuhlinzwa kwamehlo okwelapha. Ukuhlinzwa kwe-Ophthalmic ngokuvamile kwenziwa endaweni. Ukuncibilika kwamanzi nokuzinza kwe-ergothioneine kunikeza ukuba nokwenzeka kokuhlinzwa okunjalo futhi kube nenani elikhulu lesicelo.

Izinhlelo zokusebenza kwezinye izinkambu

I-Ergothioneine isetshenziswa emikhakheni eminingi ngenxa yezakhiwo zayo ezinhle kakhulu. Isibonelo, isetshenziswa emkhakheni wemithi, insimu yokudla, insimu yokunakekelwa kwezempilo, insimu yezimonyo, njll. Emkhakheni wezokwelapha, ingasetshenziswa ukwelapha ukuvuvukala, njll, futhi ingenziwa ibe amaphilisi, amaphilisi, ngomlomo. amalungiselelo, njll.; Emkhakheni wemikhiqizo yezempilo, ingavimbela ukuvela komdlavuza, njll, futhi ingenziwa ibe ukudla okusebenzayo, iziphuzo ezisebenzayo, njll.; Emkhakheni wezimonyo, ingasetshenziswa Isetshenziselwa ukulwa nokuguga futhi ingenziwa isikrini selanga neminye imikhiqizo.

Njengoba ukuqwashisa kwabantu ngokunakekelwa kwezempilo kwanda, izakhiwo ezinhle kakhulu ze-ergothioneine njengesithako esithinta imvelo kancane kancane zizoqashelwa kabanzi futhi zisetshenziswe.