Eminyakeni yamuva nje, ukusetshenziswa kwe-monobenzone njenge-ejenti esusa isikhumba kuye kwasusa inkulumompikiswano enkulu emiphakathini yezokwelapha ne-dermatological. Nakuba abanye bebhekwa njengokwelapha okusebenzayo kwezimo ezifana ne-vitiligo, abanye baphakamisa ukukhathazeka ngokuphepha kwayo kanye nemiphumela engemihle engaba khona.
I-Monobenzone, eyaziwa nangokuthi i-monobenzyl ether ye-hydroquinone (MBEH), i-ejenti esusa umbala esetshenziselwa ukukhanyisa isikhumba ngokubhubhisa unomphela ama-melanocyte, amaseli anesibopho sokukhiqiza i-melanin. Le ndawo iholele ekusetshenzisweni kwayo ekwelapheni i-vitiligo, isimo sesikhumba esingapheli esibonakala ngokulahleka kombala kuma-patches.
Abasekeli be-monobenzone baphikisa ngokuthi ingasiza abantu abane-vitiligo ukuthi bathole isikhumba esifanayo ngokukhipha umbala ezindaweni ezingathintekile ukuze zifane neziqephu ezingenambala. Lokhu kungathuthukisa ukubukeka okuphelele kanye nokuzethemba kwalabo abathintwe yilesi simo, okungaba nomthelela omkhulu eqophelweni labo lempilo.
Kodwa-ke, ukusetshenziswa kwe-monobenzone akukhona ukungqubuzana. Abagxeki bakhomba imiphumela engemihle engaba khona kanye nokukhathazeka kokuphepha okuhlobene nokusetshenziswa kwayo. Okunye okukhathazayo okuyinhloko ingozi yokukhishwa kwebala elingenakuhlehliswa, njengoba i-monobenzone iwabhubhisa unomphela ama-melanocyte. Lokhu kusho ukuthi uma ukukhishwa kwe-pigment kwenzeka, akukwazi ukuhlehliswa, futhi isikhumba sizohlala silula kulezo zindawo unomphela.
Ukwengeza, kunedatha elinganiselwe yesikhathi eside mayelana nokuphepha kwe-monobenzone, ikakhulukazi mayelana nokuba khona kwayo kwe-carcinogenicity kanye nengozi yokuzwela kwesikhumba nokucasuka. Ezinye izifundo ziphakamise ukuxhumana okungenzeka phakathi kokusetshenziswa kwe-monobenzone kanye nengozi eyengeziwe yomdlavuza wesikhumba, nakuba ucwaningo olwengeziwe luyadingeka ukuze kuqinisekiswe lokhu okutholakele.
Ngaphezu kwalokho, umthelela ongokwengqondo wokwelashwa kokususwa kwepigmentation nge-monobenzone akufanele kunganakwa. Nakuba kungase kuthuthukise ukubukeka kwesikhumba esihlaselwe yi-vitiligo, kungase futhi kubangele imizwa yokulahlekelwa ubuwena kanye nokucwaswa ngokwesiko, ikakhulukazi emiphakathini lapho umbala wesikhumba uxhumene ngokujulile nobuwena nokwamukeleka emphakathini.
Naphezu kwalokhu kukhathazeka, i-monobenzone iyaqhubeka nokusetshenziswa ekwelapheni i-vitiligo, nakuba ngokuqapha nokuqapha ngokucophelela imiphumela emibi. Odokotela besikhumba nabahlinzeki bezempilo bagcizelela ukubaluleka kokuvuma ukwaziswa kanye nemfundo ephelele yesiguli lapho kucatshangelwa ukwelashwa kwe-monobenzone, ukuqinisekisa ukuthi abantu ngabanye bayaqonda kokubili izinzuzo ezingaba khona nezingozi ezihlobene nokusetshenziswa kwakho.
Ukuqhubekela phambili, ucwaningo olwengeziwe luyadingeka ukuze kuqondwe kangcono ukuphepha kwesikhathi eside kanye nempumelelo ye-monobenzone, kanye nomthelela wayo enhlalakahleni yengqondo yeziguli. Okwamanje, odokotela kufanele balinganise izinzuzo ezingaba khona kanye nezingozi zokwelashwa kwe-monobenzone ngakunye, kucatshangelwa izimo ezihlukile zesiguli ngasinye kanye nezinto ezithandwayo.
Sengiphetha, ukusetshenziswa kwe-monobenzone njenge-ejenti yokususa isikhumba kuhlala kuyisihloko sempikiswano kanye nempikiswano phakathi komphakathi wezokwelapha. Nakuba ingase inikeze izinzuzo kubantu abane-vitiligo, ukukhathazeka ngokuphepha kwayo kanye nemiphumela yesikhathi eside kugcizelela isidingo sokucatshangelwa ngokucophelela nokuqapha lapho usebenzisa le ejenti emisebenzini yokwelapha.
Isikhathi sokuthumela: Mar-09-2024
