I-Metabolism
I-Vitamin B3, eyaziwa nangokuthi i-niacin, iyivithamini encibilikayo emanzini edlala indima ebalulekile ezinqubweni ezihlukahlukene ze-metabolic emzimbeni. Nawa amaphuzu abalulekile mayelana ne-vitamin B3:
Amafomu e-Vitamin B3:
I-Niacin ikhona ngezinhlobo ezimbili eziyinhloko: i-nicotinic acid ne-nicotinamide. Zombili lezi zinhlobo zingamanduleli kuma-coenzymes adlala indima ebalulekile kumetabolism yamandla.
Imisebenzi:
I-Niacin iyisandulela sama-coenzymes amabili: i-nicotinamide adenine dinucleotide (NAD) kanye ne-nicotinamide adenine dinucleotide phosphate (NADP). Lawa ma-coenzymes abamba iqhaza ekuphenduleni kwe-redox, edlala indima ebalulekile ekukhiqizweni kwamandla, ukulungiswa kwe-DNA, nezindlela ezahlukahlukene ze-metabolic.
Imithombo ye-Niacin:
Imithombo yokudla ye-niacin ihlanganisa:
Inyama (ikakhulukazi inkukhu, inhlanzi, nenyama enamafutha)
Amantongomane kanye nembewu
Imikhiqizo yobisi
Imifino (njengamakinati nama-lentile)
Okusanhlamvu okuphelele
Imifino
Okusanhlamvu okuqinisiwe
I-Niacin Equivalents:
Okuqukethwe kwe-niacin ekudleni kungavezwa ngokulinganayo kwe-niacin (NE). I-NE eyodwa ilingana no-1 mg we-niacin noma u-60 mg we-tryptophan, i-amino acid engaguqulwa ibe i-niacin emzimbeni.
Ukuntula:
Ukuntuleka okukhulu kwe-niacin kungaholela esimweni esaziwa ngokuthi i-pellagra, esibonakala ngezimpawu ezinjenge-dermatitis, isifo sohudo, ukuwohloka komqondo, futhi, uma kungelashwa, nokufa. I-Pellagra ayivamile emazweni athuthukile kodwa ingenzeka kubantu abangadli kahle i-niacin.
Isibonelelo Sokudla Esinconyiwe (RDA):
Umthamo onconywayo wansuku zonke we-niacin uyahlukahluka ngeminyaka, ubulili, kanye nesigaba sempilo. I-RDA iboniswa ngama-milligrams of niacin equivalents (NE).
I-Niacin nempilo yenhliziyo:
I-Niacin icwaningwe ngezinzuzo zayo ezingaba khona empilweni yenhliziyo nemithambo yegazi. Ingasiza ekukhuphuleni amazinga e-high-density lipoprotein (i-HDL noma “enhle”) ye-cholesterol futhi yehlise amazinga e-cholesterol e-low-density lipoprotein (LDL noma “embi”). Kodwa-ke, ukwesekwa kwe-niacin ngezinjongo zenhliziyo kufanele kwenziwe ngaphansi kokuqondisa kodokotela ngenxa yemiphumela engemihle engaba khona.
I-Niacin Flush:
Imithamo ephezulu ye-niacin ingabangela umphumela ongaseceleni owaziwa ngokuthi “i-niacin flush,” ebonakala ngokuba bomvu, ukufudumala, nokuluma kwesikhumba. Lena impendulo yesikhashana emiphumeleni ye-vasodilating ye-niacin futhi ayilimazi.
Ukwengeza:
I-Niacin supplementation ngokuvamile ayidingekile kubantu abanokudla okulinganiselayo. Kodwa-ke, ezimweni ezithile zezokwelapha noma ngaphansi kokuqondisa kwezokwelapha, izithasiselo ze-niacin zinganconywa.
Ukusebenzelana Nemithi:
I-Niacin ingasebenzisana nemithi ethile, okuhlanganisa imithi yomfutho wegazi, imithi yesifo sikashukela, nama-statins. Abantu abaphuza imithi kufanele baxhumane nabahlinzeki bezempilo ngaphambi kokuthatha izithasiselo ze-niacin.
Ukuqinisekisa ukudla okwanele kwe-niacin ngokudla okunomsoco kubalulekile empilweni yonke kanye nokusebenza kahle kwe-metabolic. Ezimweni lapho ukwesekwa kucatshangelwa khona, kufanele kwenziwe ngaphansi kokuqondisa kochwepheshe bezempilo.
Isikhathi sokuthumela: Jan-17-2024
