Iyini i-Fisetin?

I-Fisetini-flavonoid eyenzeka ngokwemvelo etholakala ezinhlobonhlobo zezithelo nemifino, okuhlanganisa ama-strawberries, ama-apula, amagilebhisi, u-anyanisi, namakhukhamba. Ilungu lomndeni we-flavonoid, i-fisetin yaziwa ngombala wayo ophuzi ogqamile futhi iye yaqashelwa ngezinzuzo zayo zezempilo ezingaba khona.

I-Fisetin iyi-flavonoid eyingxenye ye-flavonol subclass. Kuyinhlanganisela ye-polyphenolic enomthelela embala nasekunambithekeni kwezitshalo eziningi.I-Fisetinakuyona nje isithako sokudla kodwa futhi iyinhlanganisela ye-bioactive eye yaheha ukunaka kwesayensi ngezindawo zayo zokwelapha ezingaba khona.

I-Fisetinitholakala ikakhulukazi ezithelweni nemifino ehlukahlukene. Imithombo ecebe kakhulu ihlanganisa:

• Ama-Strawberry: Ama-Strawberries aqukethe inani eliphakeme kakhulu le-fisetin, okuwenza abe ukukhetha okumnandi nokunempilo.
• Ama-apula: Ama-apula angomunye umthombo omuhle kakhulu wale flavonoid, ikakhulukazi ikhasi.
• Amagilebhisi: Womabili amagilebhisi abomvu naluhlaza aqukethe i-fisetin, ebasiza ukuthi basebenze njenge-antioxidant.
• U-anyanisi: U-anyanisi, ikakhulukazi u-anyanisi obomvu, waziwa ngokucebile ngama-flavonoid, kuhlanganise ne-fisetin.
• Ikhukhamba: Le mifino eqabulayo nayo iqukethe i-fisetin, eyandisa izinzuzo zayo zezempilo.

Engeza lokhu kudla ekudleni kwakho kungasiza ukwandisa ukudla kwakhoi-fisetinukudla nokukhuthaza impilo yonke.

I-Fisetin iyi-antioxidant enamandla, okusho ukuthi isiza ukunciphisa ama-radicals mahhala emzimbeni. Ama-radicals wamahhala angama-molecule angazinzile angabangela ukucindezeleka okwenziwe nge-oxidative, okuholela ekulimazeni kwamangqamuzana futhi kubangele izifo ezihlukahlukene ezingapheli, kuhlanganise nomdlavuza nesifo senhliziyo. Ngokunciphisa ingcindezi ye-oxidative,i-fisetiningasiza ukuvikela amaseli futhi ikhuthaze impilo yonke.

I-Fisetin inezindawo zokulwa nokuvuvukala futhi ingasiza ekunciphiseni ukuvuvukala emzimbeni. Lo mphumela ungaba yinzuzo ikakhulukazi kubantu abanezifo ezivuvukalayo.

I-Fisetin ithole ukunakwa okukhulu ngemiphumela yayo ye-neuroprotective engaba khona. Ucwaningo luphakamisa ukuthi i-fisetin ingasiza ukuvikela amangqamuzana obuchopho emonakalweni futhi isekele ukusebenza kwengqondo. Ucwaningo luye lwabonisa ukuthi i-fisetin ingathuthukisa inkumbulo nokufunda ngokukhuthaza ukusinda kwe-neuronal nokunciphisa i-neuroinflammation. Lokhu kwenzai-fisetinisakhi esidumile sokwelapha ukwehla kwengqondo okuhlobene neminyaka kanye nezifo ze-neurodegenerative njenge-Alzheimer's.

Ucwaningo luye lwabonisa ukuthi i-fisetin ingavimbela ukukhula kwamangqamuzana omdlavuza ahlukahlukene, kuhlanganise nebele, ikholoni, namangqamuzana omdlavuza wendlala yesinye. Kubonakala sengathi kudala i-apoptosis (i-programmed cell death) kumaseli omdlavuza kuyilapho ivikela amaseli anempilo. Nakuba ucwaningo olwengeziwe ludingeka, lokhu okutholakele kugqamisa amandla e-fisetin njengendlela ehambisanayo yokwelashwa komdlavuza.

I-Fisetiningase futhi ikhuthaze impilo yenhliziyo nemithambo yegazi ngokwenza ngcono ukusebenza kwe-endothelial kanye nokwehlisa umfutho wegazi. Izakhiwo zayo ze-antioxidant kanye ne-anti-inflammatory zisiza ukuvikela isimiso senhliziyo emonakalweni, ngaleyo ndlela kunciphisa ingozi yesifo senhliziyo.

Izinzuzo zezempilo ze-fisetin zingabalelwa ezindleleni ezimbalwa zokwenza:

• Umsebenzi We-Antioxidant: I-Fisetin ingasusa ama-radicals mahhala, ithuthukise uhlelo lokuzivikela lwe-antioxidant yomzimba, futhi yehlise ingcindezi ye-oxidative.
• Ukuguqulwa kwezindlela zokubonisa: I-Fisetin ithinta izindlela ezihlukahlukene zokubonisa amaselula, kuhlanganise nalabo abathintekayo ekuvuvukeni, ukusinda kwamaseli, kanye ne-apoptosis.
• Isisho sofuzo: I-Quercetin ingalawula ukuvezwa kwezakhi zofuzo ezihlobene nokuvuvukala, ukulawulwa komjikelezo wamaseli kanye ne-apoptosis, ngaleyo ndlela yenze imiphumela yayo yokwelapha.

Ngenxa yezinzuzo zayo ezihlukahlukene zezempilo,i-fisetinicutshungulwa ngezicelo ezahlukahlukene kwezokwelapha nokunakekelwa kwezempilo. Ezinye izindawo ezingase zifake izicelo zifaka:

• I-NUTRIENTS: Izithako ze-Fisetin ziya ngokuya zithandwa njengendlela engokwemvelo yokusekela impilo nokuphila kahle.
• Impilo Yengqondo: I-Fisetin ingathuthukiswa ibe isengezo esenzelwe ukuthuthukisa inkumbulo nokusebenza kwengqondo, ikakhulukazi kubantu asebekhulile.
• Ukwelashwa Komdlavuza: Abacwaningi bafunda amandla e-fisetin njengendlela yokwelapha ehambisanayo ekwelapheni umdlavuza, ikakhulukazi ikhono layo lokukhetha amangqamuzana omdlavuza.