Isingeniso Somkhiqizo
I-Thiamidol iyisithako esinelungelo lobunikazi esilwa nombala esakhiwe ngemva kweminyaka engaphezu kweshumi yocwaningo. Lokhu okusha kwesithako esisebenzayo kuphawula inguquko ocwaningweni lokususwa kwendawo ye-pigment - umphumela we-thiamidol uqondiwe futhi uyabuyiseleka emuva, ngakho-ke imikhiqizo kutholakale ukuthi iyasebenza futhi iphephile. Ngaphambi kwalolu cwaningo, bekungenzeki ukwenza isithako esisebenzayo esisebenza ngokunembe kangaka. Ngokuphambene nalokho, kuze kube yileso sikhathi kwakungenzeka kuphela ukuvimbela ukusatshalaliswa nge-niacianamides nezinye izithako ezisebenzayo. I-Niacianamide iyodwa ayisona isivimbeli se-tyrosine yomuntu futhi iphazamisa kuphela ukudluliswa kwe-melanin.
Umsebenzi
Umphumela wokuba mhlophe we-Thiamidol ubaluleke kakhulu:
1. Ukuvinjelwa komsebenzi we-tyrosinase yabantu: I-Thiamidol ingesinye sezivimbela ezinamandla kakhulu zomsebenzi we-tyrosinase owaziwayo njengamanje, ezingavimbela ukwakheka kwe-melanin emthonjeni.
2. Iphephile futhi imnene: I-Thiamidol ayinayo i-cytotoxicity futhi iyisithako esimhlophe esiphephile nesithambile. I-Thiamidol inezinzuzo ezinhle kunezinye izithako ezimhlophe.
3. Ukusebenza kahle: I-Thiamidol ingathuthukisa ngempumelelo i-melasma ethambile, emaphakathi futhi eqinile, futhi ingathuthukisa ngempumelelo amabala ombala kanye namabala obudala.
Isitifiketi Sokuhlaziya
Igama Lomkhiqizo | I-Thiamidol | Ukucaciswa | Izinga Lenkampani |
CASCha. | 1428450-95-6 | Usuku Lokukhiqiza | 2024.7.20 |
Ubuningi | 100KG | Idethi yokuhlaziya | 2024.7.27 |
Inombolo yeqoqo. | ES-240720 | Usuku Eliphelela ngalo | 2026.7.19 |
Isisindo samangqamuzana | 278.33 | Uphawu lwamangqamuzana | C₁₈H₂₃NO₃S |
Izinto | Imininingwane | Imiphumela | |
Ukubukeka | Impushana emhlophe ukuya kokumhlophe | Iyahambisana | |
Ukuhlonza | Isikhathi sokugcina sesiqongo esikhulu sesixazululo sesampula sihambisana naleso sesixazululo esijwayelekile | Iyahambisana | |
Okuqukethwe kwamanzi | ≤1.0% | 0.20% | |
I-Residual solvent (GC) | I-acetonitrile≤0.041% | ND | |
| I-Dichloromethane≤0.06% | ND | |
| I-Toluene≤0.089% | ND | |
| I-Heptane≤0.5% | 60ppm | |
| I-Ethanol≤0.5% | ND | |
| I-Ethyl acetate≤0.5% | 1319ppm | |
| I-acetic acid≤0.5% | ND | |
Into ehlobene (HPLC) | Ukungcola Okukodwa≤1.0% | 0.27% | |
| Ingqikithi ye-Impuritics≤2.0% | 0.44% | |
Izinsalela Ekushiseni | ≤0.5% | 0.03% | |
Isivivinyo(I-HPLC) | 98.0%~102.0% | 98.5% | |
Isitoreji | Gcina esitsheni esibamba umoya, esivikelwe ekukhanyeni. | ||
Impilo yeshelufu | Iminyaka emibili uma igcinwe kahle. | ||
Isiphetho | Ufanelekile. |
Abasebenzi bokuhlola: Abasebenzi bakwa-Yan Li Buyekeza: I-Lifen Zhang Abasebenzi abagunyaziwe: LeiLiu